Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer's disease.-论文-万方医学网

第一作者： Attila,Köfalvi

第一单位： CNC - Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal; Institute for Interdisciplinary Research, University of Coimbra, Coimbra, Portugal.

作者： Attila,Köfalvi ^[1] ; Cristina,Lemos ^[2] ; Ana M,Martín-Moreno ^[3] ; Bárbara S,Pinheiro ^[2] ; Luis,García-García ^[4] ; Miguel A,Pozo ^[5] ; Ângela,Valério-Fernandes ^[2] ; Rui O,Beleza ^[2] ; Paula,Agostinho ^[6] ; Ricardo J,Rodrigues ^[1] ; Susana J,Pasquaré ^[7] ; Rodrigo A,Cunha ^[6] ; María L,de Ceballos ^[8]

作者单位： CNC - Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal; Institute for Interdisciplinary Research, University of Coimbra, Coimbra, Portugal. ^[1] CNC - Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal. ^[2] Neurodegeneration Group, Department of Cellular, Molecular and Developmental Neurobiology, Instituto Cajal, CSIC, Doctor Arce, 37, 28002 Madrid, Spain; CIBERNED; Centre for Biomedical Research on Neurodegenerative Diseases, Spain. ^[3] CAI de Cartografía Cerebral, Instituto Pluridisciplinar, UCM, Madrid, Spain. ^[4] CAI de Cartografía Cerebral, Instituto Pluridisciplinar, UCM, Madrid, Spain; PET Technology Institute, Madrid, Spain. ^[5] CNC - Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal; FMUC, Faculty of Medicine, University of Coimbra, Coimbra, Portugal. ^[6] Neurodegeneration Group, Department of Cellular, Molecular and Developmental Neurobiology, Instituto Cajal, CSIC, Doctor Arce, 37, 28002 Madrid, Spain; Instituto de Investigaciones Bioquímicas de Bahía Blanca (INIBIBB), CONICET-Bahía Blanca and Universidad Nacional del Sur, Edificio E1, Camino La Carrindanga km 7, 8000 Bahía Blanca, Argentina. ^[7] Neurodegeneration Group, Department of Cellular, Molecular and Developmental Neurobiology, Instituto Cajal, CSIC, Doctor Arce, 37, 28002 Madrid, Spain; CIBERNED; Centre for Biomedical Research on Neurodegenerative Diseases, Spain. Electronic address: mceballos@cajal.csic.es. ^[8]

主题词衰老(Aging);阿尔茨海默病(Alzheimer Disease);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);淀粉样变性(Amyloidosis);动物(Animals);花生四烯酸类(Arachidonic Acids);星形细胞(Astrocytes);脑(Brain);细胞, 培养的(Cells, Cultured);环氧化酶2(Cyclooxygenase 2);环氧化酶2抑制剂(Cyclooxygenase 2 Inhibitors);内源性大麻酚类(Endocannabinoids);葡萄糖(Glucose);羟乙基云香甙(Hydroxyethylrutoside);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);神经元(Neurons);脑代谢改善药(Nootropic Agents);多不饱和脂肪酸酰胺类(Polyunsaturated Alkamides);受体, 大麻酚, CB2(Receptor, Cannabinoid, CB2);组织培养技术(Tissue Culture Techniques)

DOI 10.1016/j.neuropharm.2016.03.015

PMID 26976670

发布时间 2018-03-08

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Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer's disease.

Neuropharmacology

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Neuropharmacology

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Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer's disease.

Neuropharmacology

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Neuropharmacology

相关期刊

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