Discovery of Novel Indoline Cholesterol Ester Transfer Protein Inhibitors (CETP) through a Structure-Guided Approach.

导出 OA

翻译打印收藏纠错

作者： Jonathan E,Wilson ^[1] ; Ravi,Kurukulasuriya ^[1] ; Mikhail,Reibarkh ^[1] ; Maud,Reiter ^[1] ; Aaron,Zwicker ^[1] ; Kake,Zhao ^[1] ; Fengqi,Zhang ^[1] ; Rajan,Anand ^[1] ; Vincent J,Colandrea ^[1] ; Anne-Marie,Cumiskey ^[2] ; Alejandro,Crespo ^[1] ; Ruth A,Duffy ^[2] ; Beth Ann,Murphy ^[2] ; Kaushik,Mitra ^[2] ; Douglas G,Johns ^[2] ; Joseph L,Duffy ^[1] ; Petr,Vachal ^[1]

作者单位： Department of Medicinal Chemistry and Department of Structural Chemistry, Merck Research Laboratories, Merck & Co, Inc. , P.O. Box 2000, Rahway, New Jersey 07065, United States. ^[1] Department of Pharmacology, Department of Drug Metabolism and Pharmacokinetics, and Department of Biology, Merck Research Laboratories, Merck & Co, Inc. , P.O. Box 2000, Kenilworth, New Jersey 07033, United States. ^[2]

关键词 CETP inhibition HDL cholesterol ester transfer protein indoline tetrahydroquinoxaline

DOI 10.1021/acsmedchemlett.5b00404

PMID 26985312

发布时间 2020-10-01

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交