Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.

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第一作者： Alejandro,Villarino

第一单位： Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, United States.

作者： Alejandro,Villarino ^[1] ; Arian,Laurence ^[1] ; Gertraud W,Robinson ^[2] ; Michael,Bonelli ^[1] ; Barbara,Dema ^[1] ; Behdad,Afzali ^[1] ; Han-Yu,Shih ^[1] ; Hong-Wei,Sun ^[1] ; Stephen R,Brooks ^[1] ; Lothar,Hennighausen ^[2] ; Yuka,Kanno ^[1] ; John J,O'Shea ^[1]

作者单位： Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, United States. ^[1] Laboratory of Genetics and Physiology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, United States. ^[2]

关键词 STAT signaling STAT5 T cells autoimmunity cell biology cytokine immunology mouse transcription factors

主题词动物(Animals);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);STAT5转录因子(STAT5 Transcription Factor)

DOI 10.7554/eLife.08384

PMID 26999798

发布时间 2018-11-13

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准确一般字义偏差语意偏离译文作用小提交