换一批
换一批Design, formulation and optimization of novel soft nano-carriers for transdermal olmesartan medoxomil delivery: In vitro characterization and in vivo pharmacokinetic assessment.
作者：
关键词
Acetonitrile (PubChem CID: 6342)Box-Behnken designCarbopol 934 (PubChem CID: 6581)Chloroform (PubChem CID: 6212)Ethanol (PubChem CID: 702)Ethylenediaminetetraacetic acid (PubChem CID: 6049)Isopropyl alcohol (PubChem CID: 3776)Methanol (PubChem CID: 887)Nano-invasomesOlmesartanOlmesartan medoxomil (PubChem CID: 130881)PharmacokineticsPhosphotungstic acid (PubChem CID: 16212977)Polyethylene glycol-400 (PubChem CID: 174)Potassium dihydrogen phosphate (PubChem CID: 516951)Rhodamine B (PubChem CID: 6694)Sodium hydroxide (PubChem CID: 14798)TransdermalTriethanolamine (PubChem CID: 7618)β-citronellene (PubChem CID: 10887985)
主题词
投药, 皮肤(Administration, Cutaneous);动物(Animals);抗高血压药(Antihypertensive Agents);生物利用度(Biological Availability);化学, 药物(Chemistry, Pharmaceutical);药物载体(Drug Carriers);药物调剂(Drug Compounding);药物释放系统(Drug Delivery Systems);半衰期(Half-Life);显微镜检查, 共焦(Microscopy, Confocal);单萜类(Monoterpenes);纳米粒子(Nanoparticles);粒子大小(Particle Size);通透性(Permeability);大鼠(Rats);大鼠, Wistar(Rats, Wistar);皮肤(Skin);皮肤吸收(Skin Absorption)
DOI
10.1016/j.ijpharm.2016.03.030
PMID
27005906
发布时间
2022-04-08
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