Whi2 enhances methylmercury toxicity in yeast via inhibition of Akr1 palmitoyltransferase activity.

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作者： Gi-Wook,Hwang ^[1] ; Toru,Fukumitsu ^[2] ; Yousuke,Ogiwara ^[2] ; Tsutomu,Takahashi ^[3] ; Nobuhiko,Miura ^[4] ; Shusuke,Kuge ^[5] ; Akira,Naganuma ^[2]

作者单位： Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan. Electronic address: gwhwang@m.tohoku.ac.jp. ^[1] Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan. ^[2] Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan; School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0232, Japan. ^[3] Division of Health Effects Research, Japan National Institute of Occupational Safety and Health, 6-21-1 Nagao, Tama-ku, Kawasaki 214-8585, Japan. ^[4] Department of Microbiology, Tohoku Pharmaceutical University, Komatsushima, Aoba-ku, Sendai 981-8558, Japan. ^[5]

关键词 Akr1 Methylmercury Palmitoyltransferase Whi2 Yeast

主题词酰基转移酶类(Acyltransferases);甲基汞化合物(Methylmercury Compounds);酿酒酵母菌(Saccharomyces cerevisiae);酿酒酵母蛋白质类(Saccharomyces cerevisiae Proteins)

DOI 10.1016/j.bbagen.2016.03.026

PMID 27015763

发布时间 2016-11-26

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