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Sequencing the GRHL3 Coding Region Reveals Rare Truncating Mutations and a Common Susceptibility Variant for Nonsyndromic Cleft Palate.

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作者单位: Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany. Electronic address: e.mangold@uni-bonn.de. [1] Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany; Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany. [2] Department of Orthodontics, University of Bonn, 53127 Bonn, Germany. [3] Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany. [4] Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany; Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany; Department of Neonatology and Pediatric Intensive Care, Children's Hospital, University of Bonn, 53113 Bonn, Germany. [5] Clinic for Maxillofacial Surgery, University Hospital Leipzig, 04103 Leipzig, Germany. [6] Department of Oral and Maxillofacial Surgery, Head and Neck Centre, Asklepios Klinik Nord, Heidberg, 22417 Hamburg, Germany. [7] Department of Oral and Maxillofacial Surgery, University of Göttingen, 37075 Göttingen, Germany. [8] Department of Orthodontics, University of Cologne, 50931 Cologne, Germany. [9] Department of Oral and Maxillo-Facial-Plastic Surgery, University of Bonn, 53111 Bonn, Germany. [10] Department of Cleft Lip and Cleft Palate Surgery, Humboldt University of Berlin, 13353 Berlin, Germany. [11] Section of Phoniatrics and Pedaudiology, Department of Otolaryngology - Head and Neck Surgery, University of Ulm, 89070 Ulm, Germany. [12] Medical Genetics and Mitochondrial Research Group, Latvian Biomedical Research and Study Centre, Riga 1067, Latvia. [13] Institute of Child Health, University College London, London WC1N 1EH, UK. [14] Institute of Human Genetics, Ulm University, 89073 Ulm, Germany. [15] Orthodontic Department, College of Dentistry, Thamar University, Thamar, Yemen. [16] Institute of Medical Biometry, Informatics and Epidemiology, University of Bonn, 53127 Bonn, Germany. [17]
DOI 10.1016/j.ajhg.2016.02.013
PMID 27018475
发布时间 2021-12-03
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American journal of human genetics

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