Zebrafish biosensor for toxicant induced muscle hyperactivity.

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作者： Maryam,Shahid ^[1] ; Masanari,Takamiya ^[2] ; Johannes,Stegmaier ^[1] ; Volker,Middel ^[3] ; Marion,Gradl ^[1] ; Nils,Klüver ^[2] ; Ralf,Mikut ^[1] ; Thomas,Dickmeis ^[4] ; Stefan,Scholz ^[3] ; Sepand,Rastegar ^[1] ; Lixin,Yang ^[4] ; Uwe,Strähle ^[1]

作者单位： Institute of Toxicology and Genetics, Karlsruhe Institute of Technology (KIT), Postfach 3640, D76021 Karlsruhe. ^[1] Faculty of Biosciences, Ruprecht-Karls-University of Heidelberg, D69120 Heidelberg, Germany. ^[2] Institute for Applied Computer Sciences, Karlsruhe Institute of Technology (KIT), Postfach 3640, D76021 Karlsruhe, Germany. ^[3] Department of Bioanalytical Ecotoxicology, UFZ - Helmholtz Centre for Environmental Research, D04318 Leipzig, Germany. ^[4] Department of Environmental Pollution and Health, State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, 100012, Beijing, China. ^[5]

主题词动物(Animals);动物, 基因修饰(Animals, Genetically Modified);谷硫磷(Azinphosmethyl);生物传感技术(Biosensing Techniques);剂量效应关系, 药物(Dose-Response Relationship, Drug);建立者效应(Founder Effect);加兰他敏(Galantamine);基因表达调控(Gene Expression Regulation);绿色荧光蛋白质类(Green Fluorescent Proteins);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);运动活动(Motor Activity);肌(Muscles);突变嵌合蛋白质类(Mutant Chimeric Proteins);脊索(Notochord);农药(Pesticides);启动区, 遗传(Promoter Regions, Genetic);甲基邻异丙氧基氨基甲酸苯酯(Propoxur);斑马鱼(Zebrafish)

DOI 10.1038/srep23768

PMID 27029555

发布时间 2018-11-13

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