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Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors.

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第一作者： Geoffrey Wayne,Krampitz

第一单位： Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305; Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University, Stanford, CA 94305; krampitz@stanford.edu irv@stanford.edu.

作者： Geoffrey Wayne,Krampitz ^[1] ; Benson M,George ^[2] ; Stephen B,Willingham ^[2] ; Jens-Peter,Volkmer ^[2] ; Kipp,Weiskopf ^[2] ; Nadine,Jahchan ^[3] ; Aaron M,Newman ^[2] ; Debashis,Sahoo ^[2] ; Allison J,Zemek ^[4] ; Rebecca L,Yanovsky ^[2] ; Julia K,Nguyen ^[2] ; Peter J,Schnorr ^[2] ; Pawel K,Mazur ^[3] ; Julien,Sage ^[3] ; Teri A,Longacre ^[4] ; Brendan C,Visser ^[5] ; George A,Poultsides ^[5] ; Jeffrey A,Norton ^[6] ; Irving L,Weissman ^[7]

作者单位： Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305; Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University, Stanford, CA 94305; krampitz@stanford.edu irv@stanford.edu. ^[1] Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University, Stanford, CA 94305; ^[2] Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305; ^[3] Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305. ^[4] Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305; ^[5] Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University, Stanford, CA 94305; ^[6] Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University, Stanford, CA 94305; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305 krampitz@stanford.edu irv@stanford.edu. ^[7]

关键词 CD47 CD90 MET cancer stem cell pancreatic neuroendocrine tumor

医学主题词动物(Animals);女(雌)性(Female);人类(Humans);同工酶类(Isoenzymes);男(雄)性(Male);小鼠, 近交NOD(Mice, Inbred NOD);小鼠, SCID(Mice, SCID);肿瘤转移(Neoplasm Metastasis);肿瘤蛋白质类(Neoplasm Proteins);神经内分泌瘤(Neuroendocrine Tumors);胰腺肿瘤(Pancreatic Neoplasms);视黄醛脱氢酶(Retinal Dehydrogenase);肿瘤逃逸(Tumor Escape);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1073/pnas.1600007113

PMID 27035983

发布时间 2021-12-03

基金项目

T32 CA009302/CA/NCI NIH HHS/United States R00 CA151673/CA/NCI NIH HHS/United States K99 CA197816/CA/NCI NIH HHS/United States Howard Hughes Medical Institute/United States P01 CA139490/CA/NCI NIH HHS/United States R00 CA197816/CA/NCI NIH HHS/United States P30 CA124435/CA/NCI NIH HHS/United States

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