miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells.
第一作者:
Sonia G,Das
第一单位:
Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, MA, 02111, USA.
作者:
医学主题词
ADAM蛋白质类(ADAM Proteins);动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因敲低技术(Gene Knockdown Techniques);人类(Humans);MAP激酶信号系统(MAP Kinase Signaling System);膜蛋白质类(Membrane Proteins);小鼠(Mice);微RNAs(MicroRNAs);肿瘤侵润(Neoplasm Invasiveness);RNA, 小分子干扰(RNA, Small Interfering)
DOI
10.1186/s13058-016-0699-z
PMID
27039296
发布时间
2024-03-25
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