换一批
换一批Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.
第一作者：
Alexander,Gusev
第一单位：
Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.;Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.
作者：
Alexander,Gusev [1]
;
Huwenbo,Shi [2]
;
Gleb,Kichaev [2]
;
Mark,Pomerantz [3]
;
Fugen,Li [4]
;
Henry W,Long [5]
;
Sue A,Ingles [6]
;
Rick A,Kittles [7]
;
Sara S,Strom [8]
;
Benjamin A,Rybicki [9]
;
Barbara,Nemesure [10]
;
William B,Isaacs [11]
;
Wei,Zheng [12]
;
Curtis A,Pettaway [13]
;
Edward D,Yeboah [14]
;
Yao,Tettey [14]
;
Richard B,Biritwum [14]
;
Andrew A,Adjei [14]
;
Evelyn,Tay [14]
;
Ann,Truelove [15]
;
Shelley,Niwa [15]
;
Anand P,Chokkalingam [16]
;
Esther M,John [17]
;
Adam B,Murphy [18]
;
Lisa B,Signorello [19]
;
John,Carpten [20]
;
M Cristina,Leske [10]
;
Suh-Yuh,Wu [10]
;
Anslem J M,Hennis [21]
;
Christine,Neslund-Dudas [9]
;
Ann W,Hsing [17]
;
Lisa,Chu [17]
;
Phyllis J,Goodman [22]
;
Eric A,Klein [23]
;
John S,Witte [24]
;
Graham,Casey [6]
;
Sam,Kaggwa [25]
;
Michael B,Cook [26]
;
Daniel O,Stram [6]
;
William J,Blot [27]
;
Rosalind A,Eeles [28]
;
Douglas,Easton [29]
;
Zsofia,Kote-Jarai [30]
;
Ali Amin,Al Olama [29]
;
Sara,Benlloch [29]
;
Kenneth,Muir [31]
;
Graham G,Giles [32]
;
Melissa C,Southey [33]
;
Liesel M,Fitzgerald [34]
;
Henrik,Gronberg [35]
;
Fredrik,Wiklund [35]
;
Markus,Aly [36]
;
Brian E,Henderson [37]
;
Johanna,Schleutker [38]
;
Tiina,Wahlfors [39]
;
Teuvo L J,Tammela [40]
;
Børge G,Nordestgaard [41]
;
Tim J,Key [42]
;
Ruth C,Travis [42]
;
David E,Neal [43]
;
Jenny L,Donovan [44]
;
Freddie C,Hamdy [45]
;
Paul,Pharoah [46]
;
Nora,Pashayan [47]
;
Kay-Tee,Khaw [48]
;
Janet L,Stanford [49]
;
Stephen N,Thibodeau [50]
;
Shannon K,McDonnell [50]
;
Daniel J,Schaid [50]
;
Christiane,Maier [51]
;
Walther,Vogel [51]
;
Manuel,Luedeke [52]
;
Kathleen,Herkommer [53]
;
Adam S,Kibel [54]
;
Cezary,Cybulski [55]
;
Dominika,Wokolorczyk [55]
;
Wojciech,Kluzniak [55]
;
Lisa,Cannon-Albright [56]
;
Craig,Teerlink [56]
;
Hermann,Brenner [57]
;
Aida K,Dieffenbach [57]
;
Volker,Arndt [58]
;
Jong Y,Park [59]
;
Thomas A,Sellers [59]
;
Hui-Yi,Lin [60]
;
Chavdar,Slavov [61]
;
Radka,Kaneva [62]
;
Vanio,Mitev [62]
;
Jyotsna,Batra [63]
;
Amanda,Spurdle [64]
;
Judith A,Clements [63]
;
Manuel R,Teixeira [65]
;
Hardev,Pandha [66]
;
Agnieszka,Michael [66]
;
Paula,Paulo [67]
;
Sofia,Maia [67]
;
Andrzej,Kierzek [66]
;
PRACTICAL consortium [68]
;
David V,Conti [69]
;
Demetrius,Albanes [70]
;
Christine,Berg [26]
;
Sonja I,Berndt [71]
;
Daniele,Campa [72]
;
E David,Crawford [73]
;
W Ryan,Diver [73]
;
Susan M,Gapstur [74]
;
J Michael,Gaziano [75]
;
Edward,Giovannucci [26]
;
Robert,Hoover [76]
;
David J,Hunter [77]
;
Mattias,Johansson [78]
;
Peter,Kraft [79]
;
Loic,Le Marchand [78]
;
Sara,Lindström [80]
;
Carmen,Navarro [70]
;
Kim,Overvad [81]
;
Elio,Riboli [82]
;
Afshan,Siddiq [73]
;
Victoria L,Stevens [83]
;
Dimitrios,Trichopoulos [84]
;
Paolo,Vineis [26]
;
Meredith,Yeager [85]
;
Gosia,Trynka [86]
;
Soumya,Raychaudhuri [68]
;
Frederick R,Schumacher [1]
;
Alkes L,Price [87]
;
Matthew L,Freedman [68]
;
Christopher A,Haiman [88]
;
Bogdan,Pasaniuc
作者单位：
Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.;Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.
[1]
Bioinformatics Interdepartmental Program, University of California Los Angeles, Los Angeles, California 90095, USA.
[2]
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts 02115, USA.
[3]
Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.;Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.
[4]
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts 02115, USA.;Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.
[5]
Department of Preventative Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA.
[6]
University of Arizona College of Medicine and University of Arizona Cancer Center, Tucson, Arizona 85721, USA.
[7]
Department of Epidemiology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
[8]
Department of Public Health Sciences, Henry Ford Hospital, Detroit, Michigan 48202, USA.
[9]
Department of Preventive Medicine, Stony Brook University, Stony Brook, New York 11794, USA.
[10]
James Buchanan Brady Urological Institute, Johns Hopkins Hospital and Medical Institution, Baltimore, Maryland 21205, USA.
[11]
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.
[12]
Department of Urology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
[13]
Korle Bu Teaching Hospital, Accra, Ghana.;University of Ghana Medical School, Accra, Ghana.
[14]
Westat, Rockville, Maryland 20850, USA.
[15]
School of Public Health, University of California, Berkeley, California 94720, USA.
[16]
Cancer Prevention Institute of California, Fremont, California 94538, USA.;Stanford University School of Medicine and Stanford Cancer Institute, Palo Alto, California 94305, USA.
[17]
Department of Urology, Northwestern University, Chicago, Illinois 60611, USA.
[18]
Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.;International Epidemiology Institute, Rockville, Maryland 20850, USA.
[19]
The Translational Genomics Research Institute, Phoenix, Arizona 85004, USA.
[20]
Department of Preventive Medicine, Stony Brook University, Stony Brook, New York 11794, USA.;Chronic Disease Research Centre and Faculty of Medical Sciences, University of the West Indies, Bridgetown, Barbados.
[21]
SWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
[22]
Glickman Urological &Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
[23]
Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California 94118, USA.;Institute for Human Genetics, University of California, San Francisco, San Francisco, California 94118, USA.
[24]
Department of Surgery, Makerere University College of Health Sciences, Kampala 94118, Uganda.
[25]
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA.
[26]
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.;International Epidemiology Institute, Rockville, Maryland 20850, USA.
[27]
The Institute of Cancer Research, Sutton SM2 5NG, UK.;Royal Marsden National Health Service (NHS) Foundation Trust, London and Sutton, UK.
[28]
Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Laboratory, Worts Causeway, Cambridge CB1 8RN, UK.
[29]
The Institute of Cancer Research, Sutton SM2 5NG, UK.
[30]
Institute of Population Health, University of Manchester, Manchester M13 9PL, UK.;Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK.
[31]
Cancer Epidemiology Centre, The Cancer Council Victoria, 615 St Kilda Road, Melbourne, Victoria 3004, Australia.;Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Victoria 3004, Australia.
[32]
Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Grattan Street, Parkville, Victoria 3010, Australia.
[33]
Cancer Epidemiology Centre, The Cancer Council Victoria, 615 St Kilda Road, Melbourne, Victoria 3004, Australia.
[34]
Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm 171 77, Sweden.
[35]
Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm 171 77, Sweden.;Department of Clinical Sciences at Danderyds Hospital, Stockholm 171 77, Sweden.
[36]
Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California 90007, USA.
[37]
Department of Medical Biochemistry and Genetics Institute of Biomedicine Kiinamyllynkatu 10, University of Turku, Turku FI-20014, Finland.;BioMediTech, University of Tampere and FimLab Laboratories, Tampere 33200, Finland.
[38]
BioMediTech, University of Tampere and FimLab Laboratories, Tampere 33200, Finland.
[39]
Department of Urology, Tampere University Hospital and Medical School, University of Tampere, Tampere 33200, Finland.
[40]
Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev Ringvej 75, Herlev DK-2730, Denmark.;Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 1165, Densmark.
[41]
Cancer Epidemiology, Nuffield Department of Population Health; University of Oxford, Oxford OX3 7LF, UK.
[42]
University of Cambridge, Department of Oncology, Addenbrooke's Hospital, Box 279, Hills Road, Cambridge CB2 0QQ.;Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.
[43]
School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK.
[44]
Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus OX1 3PN, Denmark.;Faculty of Medical Science, University of Oxford, John Radcliffe Hospital, Oxford OX1 3PN, UK.
[45]
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Strangeways Laboratory, Worts Causeway, Cambridge CB1 8RN, UK.
[46]
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Strangeways Laboratory, Worts Causeway, Cambridge CB1 8RN, UK.;University College London, Department of Applied Health Research, 1-19 Torrington Place, London WC1E 7HB, UK.
[47]
Clinical Gerontology Unit, University of Cambridge, Cambridge CB1 8RN, UK.
[48]
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.;Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington 98109, USA.
[49]
Mayo Clinic, Rochester, Minnesota 55905, USA.
[50]
Institute of Human Genetics, University Hospital Ulm, 89081 Ulm, Germany.
[51]
Department of Urology, University Hospital Ulm, 89081 Ulm, Germany.
[52]
Department of Urology, Klinikum rechts der Isar der Technischen Universitaet Muenchen, 81675 Munich, Germany.
[53]
Division of Urologic Surgery, Brigham and Womens Hospital, Dana-Farber Cancer Institute, 75 Francis Street, Boston, Massachusetts 02115, USA.
[54]
International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
[55]
Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA.;George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah 84132, USA.
[56]
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany.;German Cancer Consortium (DKTK), Heidelberg 69120, Germany.
[57]
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany.
[58]
Department of Cancer Epidemiology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, Florida 33612, USA.
[59]
Biostatistics Program, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, Florida 33612, USA.
[60]
Department of Urology and Alexandrovska University Hospital, Medical University, Sofia 1431, Bulgaria.
[61]
Department of Medical Chemistry and Biochemistry, Molecular Medicine Center, Medical University, Sofia, 2 Zdrave Str., Sofia 1431, Bulgaria.
[62]
Australian Prostate Cancer Research Centre-Qld, Institute of Health and Biomedical Innovation and School of Biomedical Science, Queensland University of Technology, Brisbane, Queensland 4000, Australia.
[63]
Molecular Cancer Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland 4000, Australia.
[64]
Department of Genetics, Portuguese Oncology Institute, Porto 4200, Portugal.;Biomedical Sciences Institute (ICBAS), University of Porto, Porto 4200, Portugal.
[65]
The University of Surrey, Guildford, Surrey GU2 7XH, UK.
[66]
Department of Genetics, Portuguese Oncology Institute, Porto 4200, Portugal.
[67]
Department of Preventive Medicine, Norris Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA.
[68]
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institute of Health, Bethesda, Maryland 20892, USA.
[69]
Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Baltimore, Maryland 21287, USA.
[70]
Genomic Epidemiology Group, German Cancer Research Center (DKFZ), 69121 Heidelberg, Germany.
[71]
Urologic Oncology, University of Colorado at Denver Health Sciences Center, Denver, Colorado 80230, USA.
[72]
Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30303, USA.
[73]
Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.;Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA.;Division of Aging, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
[74]
Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.;Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
[75]
Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.
[76]
International Agency for Research on Cancer, Lyon 69008, France.;Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, Umeå 907 36, Sweden.
[77]
Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.;Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
[78]
Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA.
[79]
Department of Epidemiology, Regional Health Authority, Murcia 30009, Spain.;CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona 28029, Spain.
[80]
Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London SW7 2AZ, UK.
[81]
Department of Genomics of Common Disease, School of Public Health, Imperial College London, London SW7 2AZ, UK.
[82]
Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, USA.;Bureau of Epidemiologic Research, Academy of Athens, Athens 106 79, Greece.;Hellenic Health Foundation, Athens 106 79, Greece.
[83]
HuGeF Foundation, Torino 10126, Italy.;School of Public Health, Imperial College London, London SW7 2AZ, UK.
[84]
Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.;Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SA, UK.
[85]
Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.;Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.;Institute of Inflammation and Repair, University of Manchester, Manchester M13 9PT, UK.
[86]
Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.;Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts 02115, USA.;Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.
[87]
Bioinformatics Interdepartmental Program, University of California Los Angeles, Los Angeles, California 90095, USA.;Departments of Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles, California, USA.;Department of Human Genetics, University of California Los Angeles, Los Angeles, California 90095, USA.
[88]
主题词
乙酰化作用(Acetylation);图集(主题)(Atlases as Topic);细胞系, 肿瘤(Cell Line, Tumor);后成说, 遗传(Epigenesis, Genetic);基因座(Genetic Loci);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);组蛋白类(Histones);人类(Humans);遗传方式(Inheritance Patterns);连锁不平衡(Linkage Disequilibrium);男(雄)性(Male);多态性, 单核苷酸(Polymorphism, Single Nucleotide);前列腺肿瘤(Prostatic Neoplasms)
DOI
10.1038/ncomms10979
PMID
27052111
发布时间
2024-03-24
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Nature communications
Nature communications
10979页
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