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Quantification of Metabolic Rearrangements During Neural Stem Cells Differentiation into Astrocytes by Metabolic Flux Analysis.

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第一作者： João V,Sá

第一单位： IBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901, Oeiras, Portugal.;Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República, 2780-157, Oeiras, Portugal.

作者： João V,Sá ^[1] ; Susanne,Kleiderman ^[2] ; Catarina,Brito ^[1] ; Ursula,Sonnewald ^[3] ; Marcel,Leist ^[2] ; Ana P,Teixeira ^[4] ; Paula M,Alves ^[5]

作者单位： IBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901, Oeiras, Portugal.;Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República, 2780-157, Oeiras, Portugal. ^[1] The Doerenkamp-Zbinden Chair of in-vitro Toxicology and Biomedicine/Alternatives to Animal Experimentation, University of Konstanz, Konstanz, Germany. ^[2] Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, 7491, Trondheim, Norway.;Department of Drug Design and Pharmacology Faculty of Health and Medical Sciences, University of Copenhagen, 2100, Copenhagen, Denmark. ^[3] IBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901, Oeiras, Portugal. anat@ibet.pt.;Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República, 2780-157, Oeiras, Portugal. anat@ibet.pt. ^[4] IBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901, Oeiras, Portugal. marques@ibet.pt.;Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Avenida da República, 2780-157, Oeiras, Portugal. marques@ibet.pt. ^[5]

关键词 Astrocytic differentiation Carbon labelling cultures Metabolic flux analysis Neural stem cells