作者:
Elizabeth C,Townsend [1]
;
Mark A,Murakami [1]
;
Alexandra,Christodoulou [1]
;
Amanda L,Christie [1]
;
Johannes,Köster [2]
;
Tiffany A,DeSouza [1]
;
Elizabeth A,Morgan [3]
;
Scott P,Kallgren [4]
;
Huiyun,Liu [1]
;
Shuo-Chieh,Wu [1]
;
Olivia,Plana [1]
;
Joan,Montero [1]
;
Kristen E,Stevenson [5]
;
Prakash,Rao [6]
;
Raga,Vadhi [6]
;
Michael,Andreeff [7]
;
Philippe,Armand [1]
;
Karen K,Ballen [8]
;
Patrizia,Barzaghi-Rinaudo [9]
;
Sarah,Cahill [1]
;
Rachael A,Clark [10]
;
Vesselina G,Cooke [9]
;
Matthew S,Davids [1]
;
Daniel J,DeAngelo [1]
;
David M,Dorfman [3]
;
Hilary,Eaton [11]
;
Benjamin L,Ebert [12]
;
Julia,Etchin [13]
;
Brant,Firestone [9]
;
David C,Fisher [1]
;
Arnold S,Freedman [1]
;
Ilene A,Galinsky [1]
;
Hui,Gao [9]
;
Jacqueline S,Garcia [1]
;
Francine,Garnache-Ottou [14]
;
Timothy A,Graubert [8]
;
Alejandro,Gutierrez [15]
;
Ensar,Halilovic [9]
;
Marian H,Harris [16]
;
Zachary T,Herbert [17]
;
Steven M,Horwitz [18]
;
Giorgio,Inghirami [19]
;
Andrew M,Intlekofer [18]
;
Moriko,Ito [9]
;
Shai,Izraeli [20]
;
Eric D,Jacobsen [1]
;
Caron A,Jacobson [1]
;
Sébastien,Jeay [9]
;
Irmela,Jeremias [21]
;
Michelle A,Kelliher [22]
;
Raphael,Koch [1]
;
Marina,Konopleva [7]
;
Nadja,Kopp [1]
;
Steven M,Kornblau [7]
;
Andrew L,Kung [23]
;
Thomas S,Kupper [10]
;
Nicole R,LeBoeuf [10]
;
Ann S,LaCasce [1]
;
Emma,Lees [9]
;
Loretta S,Li [13]
;
A Thomas,Look [13]
;
Masato,Murakami [9]
;
Markus,Muschen [24]
;
Donna,Neuberg [5]
;
Samuel Y,Ng [1]
;
Oreofe O,Odejide [1]
;
Stuart H,Orkin [13]
;
Rachel R,Paquette [25]
;
Andrew E,Place [13]
;
Justine E,Roderick [22]
;
Jeremy A,Ryan [1]
;
Stephen E,Sallan [13]
;
Brent,Shoji [26]
;
Lewis B,Silverman [13]
;
Robert J,Soiffer [1]
;
David P,Steensma [1]
;
Kimberly,Stegmaier [13]
;
Richard M,Stone [1]
;
Jerome,Tamburini [27]
;
Aaron R,Thorner [25]
;
Paul,van Hummelen [25]
;
Martha,Wadleigh [1]
;
Marion,Wiesmann [9]
;
Andrew P,Weng [28]
;
Jens U,Wuerthner [9]
;
David A,Williams [23]
;
Bruce M,Wollison [25]
;
Andrew A,Lane [1]
;
Anthony,Letai [1]
;
Monica M,Bertagnolli [24]
;
Jerome,Ritz [1]
;
Myles,Brown [2]
;
Henry,Long [2]
;
Jon C,Aster [3]
;
Margaret A,Shipp [1]
;
James D,Griffin [1]
;
David M,Weinstock [29]
作者单位:
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 450 Brookline Avenue, Dana 510B, MA 02215, USA.
[1]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 450 Brookline Avenue, Dana 510B, MA 02215, USA; Center for Functional Cancer Epigenomics, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
[2]
Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.
[3]
Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.
[4]
Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
[5]
Center for Functional Cancer Epigenomics, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
[6]
Leukemia Division, MD Anderson Cancer Center, Houston, TX 77030, USA.
[7]
Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
[8]
Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA; Novartis Institutes for Biomedical Research, 4056 Basel, Switzerland.
[9]
Department of Dermatology, Brigham and Women's Hospital, Boston, MA 02115, USA.
[10]
Office of Research and Technology Ventures, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
[11]
Department of Hematology, Brigham and Women's Hospital, Boston, MA 02115, USA.
[12]
Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
[13]
EFS Bourgogne Franche Comté, INSERM UMR1098, 25020 Besançon, France.
[14]
Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215, USA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
[15]
Department of Pathology, Boston Children's Hospital, Boston, MA 02215, USA.
[16]
Molecular Biology Core Facility, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
[17]
Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
[18]
Department of Pathology, Weill Cornell Medical College, New York, NY 10065, USA.
[19]
Functional Genomics and Leukemia Research, Sheba Medical Center, Tel Hashomer and Tel Aviv University, Ramat Gan, 52621, Israel.
[20]
Department of Gene Vectors, Helmholtz Zentrum München, German Research Center for Environmental Health, Marchioninistraße 25, 81377 Munich, Germany; Department of Pediatrics, Dr. von Hauner Children's Hospital, Ludwig Maximilians University, Lindwurmstraße 4, 80337 Munich, Germany.
[21]
Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
[22]
Department of Pediatrics, Columbia University Medical Center, New York, NY 10032, USA.
[23]
Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
[24]
Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
[25]
Department of Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA.
[26]
Université Paris Descartes, Faculté de Médecine Sorbonne Paris Cité, 75005 Paris, France.
[27]
Department of Pathology, British Columbia Cancer Research Center, Vancouver V5Z 1H8, Canada.
[28]
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 450 Brookline Avenue, Dana 510B, MA 02215, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address: dweinstock@partners.org.
[29]
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞谱系(Cell Lineage);女(雌)性(Female);基因表达谱(Gene Expression Profiling);基因, p53(Genes, p53);人类(Humans);因特网(Internet);异喹啉类(Isoquinolines);白血病(Leukemia);白血病, 实验性(Leukemia, Experimental);淋巴瘤(Lymphoma);男(雄)性(Male);小鼠(Mice);小鼠, 近交NOD(Mice, Inbred NOD);分子靶向治疗(Molecular Targeted Therapy);肿瘤蛋白质类(Neoplasm Proteins);肿瘤移植(Neoplasm Transplantation);表型(Phenotype);哌嗪类(Piperazines);前体B细胞淋巴母细胞白血病淋巴瘤(Precursor B-Cell Lymphoblastic Leukemia-Lymphoma);蛋白质组(Proteome);原癌基因蛋白质c-mdm2(Proto-Oncogene Proteins c-mdm2);随机分配(Random Allocation);随机对照试验(主题)(Randomized Controlled Trials as Topic);研究设计(Research Design);组织库(Tissue Banks);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1016/j.ccell.2016.03.008
PMID
27070704
发布时间
2021-01-03
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