AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival.

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第一作者： Rigel J,Kishton

第一单位： Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA; Department of Immunology, Duke University, Durham, NC 27710, USA; Duke Molecular Physiology Institute, Duke University, Durham, NC 27710, USA.

作者： Rigel J,Kishton ^[1] ; Carson E,Barnes ^[2] ; Amanda G,Nichols ^[1] ; Sivan,Cohen ^[1] ; Valerie A,Gerriets ^[2] ; Peter J,Siska ^[3] ; Andrew N,Macintyre ^[2] ; Pankuri,Goraksha-Hicks ^[2] ; Aguirre A,de Cubas ^[4] ; Tingyu,Liu ^[2] ; Marc O,Warmoes ^[5] ; E Dale,Abel ^[6] ; Allen Eng Juh,Yeoh ^[7] ; Timothy R,Gershon ^[8] ; W Kimryn,Rathmell ^[4] ; Kristy L,Richards ^[8] ; Jason W,Locasale ^[9] ; Jeffrey C,Rathmell ^[10]

作者单位： Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA; Department of Immunology, Duke University, Durham, NC 27710, USA; Duke Molecular Physiology Institute, Duke University, Durham, NC 27710, USA. ^[1] Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA. ^[2] Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA; Department of Immunology, Duke University, Durham, NC 27710, USA; Duke Molecular Physiology Institute, Duke University, Durham, NC 27710, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt Center for Immunobiology, Vanderbilt University, Nashville, TN 37232, USA. ^[3] Division of Hematology/Oncology, Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA. ^[4] Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA. ^[5] Department of Medicine, University of Iowa, Iowa City, IA 52242, USA. ^[6] Cancer Science Institute of Singapore, National University of Singapore, Singapore 119077, Singapore; Department of Pediatrics, National University Health System, Singapore 119228, Singapore. ^[7] UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7295, USA. ^[8] Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA; Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA. ^[9] Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA; Department of Immunology, Duke University, Durham, NC 27710, USA; Duke Molecular Physiology Institute, Duke University, Durham, NC 27710, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt Center for Immunobiology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address: jeff.rathmell@vanderbilt.edu. ^[10]