Comparison of small molecules and oligonucleotides that target a toxic, non-coding RNA.

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作者： Matthew G,Costales ^[1] ; Suzanne G,Rzuczek ^[1] ; Matthew D,Disney ^[2]

作者单位： Departments of Chemistry & Neuroscience, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, United States. ^[1] Departments of Chemistry & Neuroscience, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, United States. Electronic address: disney@scripps.edu. ^[2]

关键词 Myotonic dystrophy Oligonucleotides RNA Small molecules

主题词剂量效应关系, 药物(Dose-Response Relationship, Drug);人类(Humans);分子结构(Molecular Structure);寡核苷酸类(Oligonucleotides);RNA, 未翻译(RNA, Untranslated);小分子化合物库(Small Molecule Libraries);构效关系(Structure-Activity Relationship)

DOI 10.1016/j.bmcl.2016.04.025

PMID 27117425

发布时间 2017-11-22

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