Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials.

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第一作者： Amy J,Clippinger

第一单位： PETA International Science Consortium Ltd., London, UK. AmyJC@PISCLtd.org.uk.

作者： Amy J,Clippinger ^[1] ; Arti,Ahluwalia ^[2] ; David,Allen ^[3] ; James C,Bonner ^[4] ; Warren,Casey ^[5] ; Vincent,Castranova ^[6] ; Raymond M,David ^[7] ; Sabina,Halappanavar ^[8] ; Jon A,Hotchkiss ^[9] ; Annie M,Jarabek ^[10] ; Monika,Maier ^[11] ; William,Polk ^[3] ; Barbara,Rothen-Rutishauser ^[12] ; Christie M,Sayes ^[13] ; Phil,Sayre ^[14] ; Monita,Sharma ^[15] ; Vicki,Stone ^[16]

作者单位： PETA International Science Consortium Ltd., London, UK. AmyJC@PISCLtd.org.uk. ^[1] University of Pisa, Pisa, Italy. ^[2] Contractor Supporting the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, Integrated Laboratory Systems, Inc., Research Triangle Park, NC, USA. ^[3] North Carolina State University, Raleigh, NC, USA. ^[4] NTP Interagency Center for the Evaluation of Alternative Toxicological Methods, Raleigh, NC, USA. ^[5] West Virginia University, Morgantown, WV, USA. ^[6] BASF Corporation, Florham Park, NJ, USA. ^[7] Environmental and Radiation Health Sciences Directorate, Health Canada, Ottawa, ON, Canada. ^[8] The Dow Chemical Company, Midland, MI, USA. ^[9] U.S. Environmental Protection Agency, Research Triangle Park, NC, USA. ^[10] Evonik Industries AG, Hanau-Wolfgang, Germany. ^[11] Adolphe Merkle Institute, University of Fribourg, Fribourg, Switzerland. ^[12] Department of Environmental Science, Baylor University, Waco, TX, USA. ^[13] nanoRisk Analytics, LLC, Washington, MD, USA. ^[14] PETA International Science Consortium Ltd., London, UK. ^[15] Heriot-Watt University, Edinburgh, UK. ^[16]

关键词 In vitro testing strategies Inhalation toxicity MWCNTs Multi-walled carbon nanotubes Pulmonary fibrosis Regulatory risk assessment