换一批Synthesis of new thiazolo-celecoxib analogues as dual cyclooxygenase-2/15-lipoxygenase inhibitors: Determination of regio-specific different pyrazole cyclization by 2D NMR.
第一作者：
Eman K A,Abdelall
第一单位：
Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt. Electronic address: eman.ahmed@pharm.bsu.edu.eg.
作者：
医学主题词
动物(Animals);消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);花生四烯酸盐15-脂氧合酶(Arachidonate 15-Lipoxygenase);牛(Cattle);环化(Cyclization);环氧化酶2(Cyclooxygenase 2);环氧化酶2抑制剂(Cyclooxygenase 2 Inhibitors);脂氧合酶抑制剂(Lipoxygenase Inhibitors);磁共振波谱学(Magnetic Resonance Spectroscopy);男(雄)性(Male);吡唑类(Pyrazoles);大鼠(Rats);立体异构现象(Stereoisomerism);噻唑类(Thiazoles);溃疡(Ulcer)
DOI
10.1016/j.ejmech.2016.04.049
PMID
27131067
发布时间
2022-04-09
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