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Antitumor cytotoxicity induced by bone-marrow-derived antigen-presenting cells is facilitated by the tumor suppressor protein p53 via regulation of IL-12.

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第一作者： Tania L,Slatter

第一单位： Department of Pathology, Dunedin School of Medicine, University of Otago , Dunedin, New Zealand.

作者： Tania L,Slatter ^[1] ; Michelle,Wilson ^[2] ; Chingwen,Tang ^[3] ; Hamish G,Campbell ^[4] ; Vernon K,Ward ^[3] ; Vivienne L,Young ^[3] ; David,Van Ly ^[4] ; Nicholas I,Fleming ^[1] ; Antony W,Braithwaite ^[5] ; Margaret A,Baird ^[6]

作者单位： Department of Pathology, Dunedin School of Medicine, University of Otago , Dunedin, New Zealand. ^[1] Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand; Department of Microbiology and Immunology, School of Medical Sciences, University of Otago, Dunedin, New Zealand. ^[2] Department of Microbiology and Immunology, School of Medical Sciences, University of Otago , Dunedin, New Zealand. ^[3] Children's Medical Research Institute, University of Sydney , Westmead, Australia. ^[4] Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand; Children's Medical Research Institute, University of Sydney, Westmead, Australia; Maurice Wilkins Center, Auckland, New Zealand. ^[5] Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand; Maurice Wilkins Center, Auckland, New Zealand. ^[6]

关键词 Cytotoxic immune response dendritic cells interleukin 12 p53 tumor suppressor protein tumor vaccination

DOI 10.1080/2162402X.2015.1112941

PMID 27141366

发布时间 2021-01-12

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