PERK mediates the IRES-dependent translational activation of mRNAs encoding angiogenic growth factors after ischemic stress.

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作者： Céline,Philippe ^[1] ; Alexandre,Dubrac ^[1] ; Cathy,Quelen ^[1] ; Aurore,Desquesnes ^[2] ; Loic,Van Den Berghe ^[3] ; Christèle,Ségura ^[3] ; Thomas,Filleron ^[4] ; Stéphane,Pyronnet ^[5] ; Hervé,Prats ^[1] ; Pierre,Brousset ^[6] ; Christian,Touriol ^[7]

作者单位： INSERM, UMR 1037, CRCT (Cancer Research Center of Toulouse), F-31037 Toulouse, France. Université Toulouse III Paul Sabatier, F-31000 Toulouse, France. ^[1] INSERM US006, CREFRE (Centre régional d'exploration fonctionnelle et de ressources expérimentales), F-31000 Toulouse, France. ^[2] INSERM, UMR 1037, CRCT (Cancer Research Center of Toulouse), F-31037 Toulouse, France. Université Toulouse III Paul Sabatier, F-31000 Toulouse, France. Vectorology Platform, CRCT Technological Pole, F-31037 Toulouse, France. ^[3] Clinical Trial Office, Department of Statistics, IUCT (Institut Universitaire du Cancer de Toulouse)-Oncopole, F-31100 Toulouse, France. ^[4] INSERM, UMR 1037, CRCT (Cancer Research Center of Toulouse), F-31037 Toulouse, France. Université Toulouse III Paul Sabatier, F-31000 Toulouse, France. Laboratoire d'Excellence Toulouse Cancer (TOUCAN), F-31037 Toulouse, France. ^[5] INSERM, UMR 1037, CRCT (Cancer Research Center of Toulouse), F-31037 Toulouse, France. Université Toulouse III Paul Sabatier, F-31000 Toulouse, France. Laboratoire d'Excellence Toulouse Cancer (TOUCAN), F-31037 Toulouse, France. Department of Pathology, IUCT-Oncopole, F-31100 Toulouse, France. ^[6] INSERM, UMR 1037, CRCT (Cancer Research Center of Toulouse), F-31037 Toulouse, France. Université Toulouse III Paul Sabatier, F-31000 Toulouse, France. christian.touriol@inserm.fr. ^[7]