Bifunctional CYP81AA proteins catalyse identical hydroxylations but alternative regioselective phenol couplings in plant xanthone biosynthesis.
第一作者:
Islam,El-Awaad
第一单位:
Institute of Pharmaceutical Biology, Technische Universität Braunschweig, Mendelssohnstraße 1, Braunschweig 38106, Germany.;Center of Pharmaceutical Engineering (PVZ), Technische Universität Braunschweig, Franz-Liszt-Straße 35A, Braunschweig 38106, Germany.
作者:
主题词
氨基酸序列(Amino Acid Sequence);生物催化(Biocatalysis);生物合成途径(Biosynthetic Pathways);细胞, 培养的(Cells, Cultured);细胞色素P450酶系统(Cytochrome P-450 Enzyme System);羟基化(Hydroxylation);金丝桃属(Hypericum);突变(Mutation);酚(Phenol);植物蛋白质类(Plant Proteins);序列同源性, 氨基酸(Sequence Homology, Amino Acid);立体异构现象(Stereoisomerism);山吨类(Xanthones)
DOI
10.1038/ncomms11472
PMID
27145837
发布时间
2018-11-13
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Nature communications
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