Neurotoxicity screening of (illicit) drugs using novel methods for analysis of microelectrode array (MEA) recordings.

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作者： L,Hondebrink ^[1] ; A H A,Verboven ^[2] ; W S,Drega ^[2] ; S,Schmeink ^[2] ; M W G D M,de Groot ^[2] ; R G D M,van Kleef ^[2] ; F M J,Wijnolts ^[2] ; A,de Groot ^[2] ; J,Meulenbelt ^[3] ; R H S,Westerink ^[2]

作者单位： National Poisons Information Center (NVIC), University Medical Center Utrecht, P.O. Box 85500, NL-3508 GA Utrecht, The Netherlands. Electronic address: L.Hondebrink@umcutrecht.nl. ^[1] Neurotoxicology Research Group, Division Toxicology, Institute for Risk Assessment Sciences (IRAS), Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.177, NL-3508 Utrecht, The Netherlands. ^[2] National Poisons Information Center (NVIC), University Medical Center Utrecht, P.O. Box 85500, NL-3508 GA Utrecht, The Netherlands; Neurotoxicology Research Group, Division Toxicology, Institute for Risk Assessment Sciences (IRAS), Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.177, NL-3508 Utrecht, The Netherlands; Department of Intensive Care Medicine, University Medical Center Utrecht, P.O. Box 85500, NL-3508 GA, Utrecht, The Netherlands. ^[3]

关键词 Analysis strategy Characterisation Illicit drugs Integrated testing strategy Neurotoxicity screening