De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.

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第一作者： Scott E,Boyken

第一单位： Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. Institute for Protein Design, University of Washington, Seattle, WA 98195, USA. Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.

作者： Scott E,Boyken ^[1] ; Zibo,Chen ^[2] ; Benjamin,Groves ^[3] ; Robert A,Langan ^[4] ; Gustav,Oberdorfer ^[5] ; Alex,Ford ^[4] ; Jason M,Gilmore ^[4] ; Chunfu,Xu ^[4] ; Frank,DiMaio ^[4] ; Jose Henrique,Pereira ^[6] ; Banumathi,Sankaran ^[7] ; Georg,Seelig ^[8] ; Peter H,Zwart ^[9] ; David,Baker ^[10]

作者单位： Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. Institute for Protein Design, University of Washington, Seattle, WA 98195, USA. Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA. ^[1] Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. Institute for Protein Design, University of Washington, Seattle, WA 98195, USA. Graduate Program in Biological Physics, Structure, and Design, University of Washington, Seattle, WA 98195, USA. ^[2] Department of Electrical Engineering, University of Washington, Seattle, WA 98195, USA. ^[3] Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. Institute for Protein Design, University of Washington, Seattle, WA 98195, USA. ^[4] Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. Institute for Protein Design, University of Washington, Seattle, WA 98195, USA. Department of Computer Science and Engineering, University of Washington, Seattle, WA 98195, USA. ^[5] Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50/3, 8010-Graz, Austria. Joint BioEnergy Institute, Emeryville, CA 94608, USA. ^[6] Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. ^[7] Department of Electrical Engineering, University of Washington, Seattle, WA 98195, USA. Berkeley Center for Structural Biology, Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA. ^[8] Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. The Center for Advanced Mathematics for Energy Research Applications, Lawrence Berkeley National Laboratories, 1 Cyclotron Road, Berkeley, CA 94720, USA. ^[9] Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. Institute for Protein Design, University of Washington, Seattle, WA 98195, USA. Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA. dabaker@u.washington.edu. ^[10]