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Glucagon-Like Peptide-1 Receptor Agonists: Beta-Cell Protection or Exhaustion?

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第一作者： Daniël H,van Raalte

第一单位： Diabetes Center, Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands; Department of Pathology and Laboratory Medicine, Child and Family Research Institute, The University of British Columbia, Vancouver, Canada. Electronic address: d.vanraalte@vumc.nl.

作者： Daniël H,van Raalte ^[1] ; C Bruce,Verchere ^[2]

作者单位： Diabetes Center, Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands; Department of Pathology and Laboratory Medicine, Child and Family Research Institute, The University of British Columbia, Vancouver, Canada. Electronic address: d.vanraalte@vumc.nl. ^[1] Department of Pathology and Laboratory Medicine, Child and Family Research Institute, The University of British Columbia, Vancouver, Canada; Department of Surgery, Child and Family Research Institute, The University of British Columbia, Vancouver, Canada. ^[2]

关键词 Glucagon-like peptide (GLP)-1 receptor agonists beta-cell exhaustion beta-cell protection chronic treatment insulin secretion

主题词动物(Animals);胰高血糖素样肽1(Glucagon-Like Peptide 1);人类(Humans);胰岛素(Insulin);胰岛素分泌细胞(Insulin-Secreting Cells);信号传导(Signal Transduction)

DOI 10.1016/j.tem.2016.04.009

PMID 27160799

发布时间 2025-01-03

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