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Impact of CYP2E1, GSTA1 and GSTP1 gene variants on serum alpha glutathione S-transferase level in patients undergoing anaesthesia.

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第一作者： Adam,Mikstacki

第一单位： Department of Anaesthesiology and Intensive Therapy, Regional Hospital, Juraszow 7/19, 60-479, Poznan, Poland.

作者： Adam,Mikstacki ^[1] ; Marzena,Skrzypczak-Zielinska ^[2] ; Oliwia,Zakerska-Banaszak ^[3] ; Barbara,Tamowicz ^[1] ; Maria,Skibinska ^[4] ; Marta,Molinska-Glura ^[5] ; Marlena,Szalata ^[6] ; Ryszard,Slomski ^[7]

作者单位： Department of Anaesthesiology and Intensive Therapy, Regional Hospital, Juraszow 7/19, 60-479, Poznan, Poland. ^[1] Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, 60-479, Poznan, Poland. ^[2] Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, 60-479, Poznan, Poland.;The NanoBioMedical Centre, Adam Mickiewicz University, Umultowska 85, 61-614, Poznan, Poland. ^[3] Department of Genetics in Psychiatry, University of Medical Sciences, Szpitalna 27/33, 60-572, Poznan, Poland. ^[4] Department of Computer Science and Statistics, University of Medical Sciences, Dabrowskiego 79, 60-529, Poznan, Poland. ^[5] Department of Biochemistry and Biotechnology, University of Life Sciences, Dojazd 11, 60-632, Poznan, Poland. ^[6] Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, 60-479, Poznan, Poland. slomski@up.poznan.pl.;Department of Biochemistry and Biotechnology, University of Life Sciences, Dojazd 11, 60-632, Poznan, Poland. slomski@up.poznan.pl. ^[7]

关键词 CYP2E1 GSTA1 GSTP1 Hepatotoxicity Polymorphism Sevoflurane α-GST