GSH-targeted nanosponges increase doxorubicin-induced toxicity "in vitro" and "in vivo" in cancer cells with high antioxidant defenses.

导出 LinkOut

翻译打印收藏纠错

第一作者： Martina,Daga

第一单位： Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy.

作者： Martina,Daga ^[1] ; Chiara,Ullio ^[1] ; Monica,Argenziano ^[2] ; Chiara,Dianzani ^[2] ; Roberta,Cavalli ^[2] ; Francesco,Trotta ^[3] ; Carlo,Ferretti ^[2] ; Gian Paolo,Zara ^[2] ; Casimiro L,Gigliotti ^[4] ; Eric S,Ciamporcero ^[1] ; Piergiorgio,Pettazzoni ^[1] ; Denise,Corti ^[5] ; Stefania,Pizzimenti ^[6] ; Giuseppina,Barrera ^[1]

作者单位： Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy. ^[1] Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, 10125 Turin, Italy. ^[2] Department of Chemistry - University of Turin, Via Pietro Giuria 7, 10125 Turin, Italy. ^[3] Department of Health Sciences, University of Eastern Piedmont'A Avogadro', Via Solaroli 17, 28100 Novara, Italy. ^[4] Department of Experimental and Clinical Biomedical Sciences, Biochemistry, Human Health Medical School University of Florence, Viale Morgagni 50, 50134 Florence, Italy. ^[5] Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy. Electronic address: stefania.pizzimenti@unito.it. ^[6]

关键词 Doxorubicin GSH-targeted nanosponges Prostate and colon cancer cells Toxic effects