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Variants within the SP110 nuclear body protein modify risk of canine degenerative myelopathy.

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第一作者： Emma L,Ivansson

第一单位： Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, 751 23 Uppsala, Sweden; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02142; emma.ivansson@ki.se kersli@broadinstitute.org.

作者： Emma L,Ivansson ^[1] ; Kate,Megquier ^[2] ; Sergey V,Kozyrev ^[3] ; Eva,Murén ^[3] ; Izabella Baranowska,Körberg ^[4] ; Ross,Swofford ^[5] ; Michele,Koltookian ^[5] ; Noriko,Tonomura ^[6] ; Rong,Zeng ^[7] ; Ana L,Kolicheski ^[7] ; Liz,Hansen ^[7] ; Martin L,Katz ^[8] ; Gayle C,Johnson ^[7] ; Gary S,Johnson ^[7] ; Joan R,Coates ^[9] ; Kerstin,Lindblad-Toh ^[1]

作者单位： Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, 751 23 Uppsala, Sweden; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02142; emma.ivansson@ki.se kersli@broadinstitute.org. ^[1] Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, 751 23 Uppsala, Sweden; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02142; ^[2] Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, 751 23 Uppsala, Sweden; ^[3] Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, 750 07 Uppsala, Sweden; ^[4] Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02142; ^[5] Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02142; Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536; ^[6] Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211; ^[7] Mason Eye Institute, School of Medicine, University of Missouri, Columbia, MO 65201; ^[8] Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211. ^[9]

关键词 ALS SOD1 SP110 amyotrophic lateral sclerosis degenerative myelopathy