换一批Structure-function characterization of the human mitochondrial thiamin pyrophosphate transporter (hMTPPT; SLC25A19): Important roles for Ile(33), Ser(34), Asp(37), His(137) and Lys(291).
第一作者：
Subrata,Sabui
第一单位：
Department of Medical Research, VA Medical Center, Long Beach, CA 90822, United States; Departments of Medicine and Physiology/Biophysics, University of California, Irvine, CA 92697, United States.
作者：
医学主题词
氨基酸序列(Amino Acid Sequence);氨基酸取代(Amino Acid Substitution);氨基酸类(Amino Acids);生物转运(Biological Transport);保守序列(Conserved Sequence);Hep G2细胞(Hep G2 Cells);人类(Humans);亲水和疏水相互作用(Hydrophobic and Hydrophilic Interactions);膜转运蛋白质类(Membrane Transport Proteins);线粒体(Mitochondria);线粒体膜转运蛋白质类(Mitochondrial Membrane Transport Proteins);模型, 分子(Models, Molecular);诱变, 定点(Mutagenesis, Site-Directed);蛋白质构象(Protein Conformation);蛋白质稳定性(Protein Stability);序列比对(Sequence Alignment);序列同源性, 氨基酸(Sequence Homology, Amino Acid);静电(Static Electricity);构效关系(Structure-Activity Relationship);底物特异性(Substrate Specificity);硫胺素焦磷酸盐(Thiamine Pyrophosphate)
DOI
10.1016/j.bbamem.2016.05.011
PMID
27188525
发布时间
2020-12-09
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