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首页> International immunopharmacology> Rhodioloside ameliorates depressive behavior via up-regulation of monoaminergic system activity and anti-inflammatory effect in olfactory bulbectomized rats.

Rhodioloside ameliorates depressive behavior via up-regulation of monoaminergic system activity and anti-inflammatory effect in olfactory bulbectomized rats.

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作者： Xu,Zhang ^[1] ; Qianming,Du ^[2] ; Chao,Liu ^[3] ; Yan,Yang ^[4] ; Jianing,Wang ^[5] ; Suqian,Duan ^[6] ; Junguo,Duan ^[7]

作者单位： Clinical Medical College, Chengdu University of TCM, Chengdu 610075, China. ^[1] General Clinical Research Center, First Affiliated Hospital of Nanjing Medical University, Nanjing, China. ^[2] Department of Pharmacy, First Affiliated Hospital of Nanjing Medical University, Nanjing, China. ^[3] Department of Traditional Chinese Medicine, The Third People's Hospital of Chengdu, 82 Qing Long Street, Chengdu 610031, China. ^[4] Neurobiology Laboratory, Jiangsu Center for Drug Screening, China Pharmaceutical University, Jiangsu, Nanjing 210009, China. ^[5] University College London, United Kingdom. ^[6] Department of Ophthalmology, Chengdu University of TCM, Chengdu 610075, China. Electronic address: jgduan2016@163.com. ^[7]

关键词 Depression Monoaminergic system NF-κB Olfactory bulbectomy Pro-inflammatory cytokine Rhodioloside

主题词动物(Animals);消炎药(Anti-Inflammatory Agents);抗抑郁药(Antidepressive Agents);生物源单胺类(Biogenic Monoamines);抑郁(Depression);疾病模型, 动物(Disease Models, Animal);葡糖苷类(Glucosides);白细胞介素1β(Interleukin-1beta);白细胞介素6(Interleukin-6);男(雄)性(Male);NF-κB(NF-kappa B);嗅球(Olfactory Bulb);酚类(Phenols);额叶前皮质(Prefrontal Cortex);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);红景天属(Rhodiola);信号传导(Signal Transduction)

DOI 10.1016/j.intimp.2016.05.008

PMID 27214337

发布时间 2017-08-05

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International immunopharmacology

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