换一批Genetically engineered pre-microRNA-34a prodrug suppresses orthotopic osteosarcoma xenograft tumor growth via the induction of apoptosis and cell cycle arrest.
第一作者：
Yong,Zhao
第一单位：
Department of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.;Department of Biochemistry &Molecular Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA.
作者：
医学主题词
动物(Animals);骨肿瘤(Bone Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);遗传工程(Genetic Engineering);人类(Humans);男(雄)性(Male);小鼠, 裸(Mice, Nude);微RNAs(MicroRNAs);肿瘤蛋白质类(Neoplasm Proteins);骨肉瘤(Osteosarcoma);药物前体(Prodrugs);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1038/srep26611
PMID
27216562
发布时间
2020-06-29
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