Anti-NGF monoclonal antibody muMab 911 does not deplete neurons in the superior cervical ganglia of young or old adult rats.

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作者： John,Marcek ^[1] ; Carlin,Okerberg ^[1] ; Chang-Ning,Liu ^[1] ; David,Potter ^[1] ; Paul,Butler ^[2] ; Magalie,Boucher ^[1] ; Mark,Zorbas ^[2] ; Peter,Mouton ^[3] ; Jens R,Nyengaard ^[4] ; Chris,Somps ^[5]

作者单位： Drug Safety R&D, Pfizer Worldwide R&D, Groton, CT, 06340, United States. ^[1] Drug Safety R&D, Pfizer Worldwide R&D, La Jolla, CA, 92121, United States. ^[2] Stereology Research Center, Inc., Tampa-St Petersburg, FL, 33741, United States. ^[3] Stereology and Electron Microscopy Laboratory, Centre for Stochastic Geometry and Advanced Bioimaging, Department of Clinical Medicine, Aarhus University, Denmark. ^[4] Drug Safety R&D, Pfizer Worldwide R&D, Groton, CT, 06340, United States. Electronic address: christopher.j.somps@pfizer.com. ^[5]

关键词 Nerve growth factor Neuron number Neuron volume Stereology Sympathetic nervous system

DOI 10.1016/j.jchemneu.2016.05.007

PMID 27233661

发布时间 2019-11-20

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