Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children.
作者:
Kenyan Bacteraemia Study Group [1]
;
Wellcome Trust Case Control Consortium 2 (WTCCC2) [2]
;
Anna,Rautanen [2]
;
Matti,Pirinen [3]
;
Tara C,Mills [2]
;
Kirk A,Rockett [2]
;
Amy,Strange [2]
;
Anne W,Ndungu [4]
;
Vivek,Naranbhai [2]
;
James J,Gilchrist [2]
;
Céline,Bellenguez [2]
;
Colin,Freeman [5]
;
Gavin,Band [5]
;
Suzannah J,Bumpstead [2]
;
Sarah,Edkins [5]
;
Eleni,Giannoulatou [5]
;
Emma,Gray [5]
;
Serge,Dronov [5]
;
Sarah E,Hunt [2]
;
Cordelia,Langford [2]
;
Richard D,Pearson [2]
;
Zhan,Su [6]
;
Damjan,Vukcevic [6]
;
Alex W,Macharia [6]
;
Sophie,Uyoga [6]
;
Carolyne,Ndila [6]
;
Neema,Mturi [6]
;
Patricia,Njuguna [6]
;
Shebe,Mohammed [6]
;
James A,Berkley [6]
;
Isaiah,Mwangi [6]
;
Salim,Mwarumba [6]
;
Barnes S,Kitsao [7]
;
Brett S,Lowe [6]
;
Susan C,Morpeth [8]
;
Iqbal,Khandwalla [9]
;
Kilifi Bacteraemia Surveillance Group [10]
;
Jenefer M,Blackwell [11]
;
Elvira,Bramon [12]
;
Matthew A,Brown [13]
;
Juan P,Casas [14]
;
Aiden,Corvin [15]
;
Audrey,Duncanson [16]
;
Janusz,Jankowski [17]
;
Hugh S,Markus [18]
;
Christopher G,Mathew [19]
;
Colin N A,Palmer [20]
;
Robert,Plomin [21]
;
Stephen J,Sawcer [22]
;
Richard C,Trembath [5]
;
Ananth C,Viswanathan [5]
;
Nicholas W,Wood [23]
;
Panos,Deloukas [7]
;
Leena,Peltonen [24]
;
Thomas N,Williams [25]
;
J Anthony G,Scott [26]
;
Stephen J,Chapman [25]
;
Peter,Donnelly ;
Adrian V S,Hill ;
Chris C A,Spencer
作者单位:
Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK. Electronic address: anna.rautanen@well.ox.ac.uk.
[1]
Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
[2]
Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
[3]
Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Department of Paediatrics, University of Oxford, Oxford OX3 9DU, UK.
[4]
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
[5]
KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
[6]
KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya; Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 9DU, UK; Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
[7]
Cambridge Institute for Medical Research and Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK; Telethon Kids Institute, The University of Western Australia, Subiaco, WA 6008, Australia.
[8]
National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health at the South London and Maudsley National Health Service (NHS) Foundation Trust and Institute of Psychiatry, King's College London, Denmark Hill, London SE5 8AF, UK.
[9]
Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
[10]
Farr Institute of Health Informatics, University College London, London NW1 2DA, UK.
[11]
Neuropsychiatric Genetics Research Group, Institute of Molecular Medicine, Trinity College Dublin, Dublin 2, Ireland.
[12]
Molecular and Physiological Sciences, The Wellcome Trust, London NW1 2BE, UK.
[13]
Associate Deans Office, John Bull Building, Peninsula School of Medicine and Dentistry, Plymouth PL6 8BU, UK.
[14]
Department of Neurology, University of Cambridge, Cambridge CB2 0QQ, UK.
[15]
Division of Genetics and Molecular Medicine, King's College London, London SE1 9RT, UK; Sydney Brenner Institute for Molecular Bioscience, University of Witwatersrand, Johannesburg 2193, South Africa.
[16]
Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
[17]
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, De Crespigny Park, London SE5 8AF, UK.
[18]
Department of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
[19]
London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK.
[20]
NIHR Biomedical Research Centre at Moorfields Eye Hospital NHSFT and UCL Institute of Ophthalmology, London EC1V 2PD, UK.
[21]
Department of Molecular Neuroscience, Institute of Neurology, Queen Square, London WC1N 3BG, UK.
[22]
KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya; Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 9DU, UK; Department of Medicine, Imperial College, London W21NY, UK; INDEPTH Network, Accra, Ghana.
[23]
Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Oxford Centre for Respiratory Medicine, Churchill Hospital Site, Oxford University Hospitals, Oxford OX3 7LE, UK.
[24]
Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Department of Statistics, University of Oxford, Oxford OX1 3TG, UK.
[25]
Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK.
[26]
主题词
青少年(Adolescent);菌血症(Bacteremia);病例对照研究(Case-Control Studies);儿童(Child);儿童, 学龄前(Child, Preschool);全基因组关联研究(Genome-Wide Association Study);人类(Humans);婴儿(Infant);婴儿, 新生(Infant, Newborn);肯尼亚(Kenya);肺炎, 肺炎球菌性(Pneumonia, Pneumococcal);多态现象, 遗传(Polymorphism, Genetic);危险因素(Risk Factors);肺炎链球菌(Streptococcus pneumoniae)
DOI
10.1016/j.ajhg.2016.03.025
PMID
27236921
发布时间
2022-11-11
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American journal of human genetics
American journal of human genetics
1092-1100页
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