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Induction of specific neuron types by overexpression of single transcription factors.

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第一作者： Yusuke,Teratani-Ota

第一单位： Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.;Department of Psychology, Center for Neuroscience, UC Davis, Davis, 95616, USA.

作者： Yusuke,Teratani-Ota ^[1] ; Kohei,Yamamizu ^[2] ; Yulan,Piao ^[3] ; Lioudmila,Sharova ^[3] ; Misa,Amano ^[4] ; Hong,Yu ^[4] ; David,Schlessinger ^[3] ; Minoru S H,Ko ^[5] ; Alexei A,Sharov ^[6]

作者单位： Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.;Department of Psychology, Center for Neuroscience, UC Davis, Davis, 95616, USA. ^[1] Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.;Laboratory of Stem Cell Differentiation, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan. ^[2] Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA. ^[3] Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.;Elixirgen, LLC, Baltimore, MD, 21205, USA. ^[4] Department of Systems Medicine, Sakaguchi Laboratory, Keio University School of Medicine, Tokyo, 160-8582, Japan. ^[5] Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA. sharoval@mail.nih.gov. ^[6]

关键词 Ascl1 Cholinergic neurons Dopaminergic neurons ESCs GABAergic neurons Gene expression profiling miRNA