首页> Innate immunity> Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages in vitro and adjuvant activity in vivo.

Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages in vitro and adjuvant activity in vivo.

导出 OA

翻译打印收藏纠错

第一作者： Alexandra,Huber

第一单位： Institute of Clinical Microbiology, Immunology and Hygiene, University Hospital Erlangen, Friedrich Alexander Universität Erlangen-Nürnberg, Berlin, Germany.

作者： Alexandra,Huber ^[1] ; Rie S,Kallerup ^[2] ; Karen S,Korsholm ^[3] ; Henrik,Franzyk ^[4] ; Bernd,Lepenies ^[5] ; Dennis,Christensen ^[3] ; Camilla,Foged ^[6] ; Roland,Lang ^[7]

作者单位： Institute of Clinical Microbiology, Immunology and Hygiene, University Hospital Erlangen, Friedrich Alexander Universität Erlangen-Nürnberg, Berlin, Germany. ^[1] Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark Department of Infectious Disease Immunology, Vaccine Adjuvant Research, Statens Serum Institut, Copenhagen, Denmark. ^[2] Department of Infectious Disease Immunology, Vaccine Adjuvant Research, Statens Serum Institut, Copenhagen, Denmark. ^[3] Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. ^[4] Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany Institute of Chemistry and Biochemistry, Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin, Berlin, Germany Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Hannover, Germany. ^[5] Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark camilla.foged@sund.ku.dk. ^[6] Institute of Clinical Microbiology, Immunology and Hygiene, University Hospital Erlangen, Friedrich Alexander Universität Erlangen-Nürnberg, Berlin, Germany roland.lang@uk-erlangen.de. ^[7]

关键词 C-type lectin receptor Mincle Vaccine adjuvant trehalose dimycolate