Deferasirox, an oral iron chelator, prevents hepatocarcinogenesis and adverse effects of sorafenib.

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第一作者： Naoki,Yamamoto

第一单位： Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, Yamaguchi 755-8505, Japan; Yamaguchi University Health Administration Center, 1677-1 Yoshida, Yamaguchi, Yamaguchi 753-8511, Japan.

作者： Naoki,Yamamoto ^[1] ; Takahiro,Yamasaki ^[2] ; Taro,Takami ^[3] ; Koichi,Uchida ^[4] ; Koichi,Fujisawa ^[5] ; Toshihiko,Matsumoto ^[2] ; Issei,Saeki ^[3] ; Shuji,Terai ^[6] ; Isao,Sakaida ^[3]

作者单位： Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, Yamaguchi 755-8505, Japan; Yamaguchi University Health Administration Center, 1677-1 Yoshida, Yamaguchi, Yamaguchi 753-8511, Japan. ^[1] Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, Yamaguchi 755-8505, Japan; Department of Oncology and Laboratory Medicine, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, Yamaguchi 755-8505, Japan. ^[2] Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, Yamaguchi 755-8505, Japan. ^[3] Department of Human Nutrition Faculty of Nursing and Human Nutrition, Yamaguchi Prefectural University, 3-2-1 Sakurabatake, Yamaguchi, Yamaguchi 753-8502, Japan. ^[4] Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, Yamaguchi 755-8505, Japan; Center of Research and Education for Regenerative Medicine, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, Yamaguchi 755-8505, Japan. ^[5] Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachidori, Chuo-Ku, Niigata 951-8510, Japan. ^[6]

关键词 deferasirox hand-foot skin syndrome liver cancer liver fibrosis sorafenib

DOI 10.3164/jcbn.15-127

PMID 27257345

发布时间 2022-03-18

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