Long-term cardiovascular outcomes and overall survival of early-stage breast cancer patients with early discontinuation of trastuzumab: a population-based study.

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第一作者： Inna Y,Gong

第一单位： University of Toronto, Toronto, ON, Canada.

作者： Inna Y,Gong ^[1] ; Sunil,Verma ^[2] ; Andrew T,Yan ^[3] ; Dennis T,Ko ^[4] ; Craig C,Earle ^[5] ; George A,Tomlinson ^[6] ; Maureen E,Trudeau ^[2] ; Murray D,Krahn ^[7] ; Monika K,Krzyzanowska ^[8] ; Christine B,Brezden-Masley ^[3] ; Scott,Gavura ^[9] ; Stuart,Peacock ^[10] ; Kelvin K W,Chan ^[11]

作者单位： University of Toronto, Toronto, ON, Canada. ^[1] University of Toronto, Toronto, ON, Canada.;Sunnybrook Health Sciences Centre, Toronto, ON, Canada. ^[2] University of Toronto, Toronto, ON, Canada.;St. Michael's Hospital, Toronto, ON, Canada. ^[3] University of Toronto, Toronto, ON, Canada.;Sunnybrook Health Sciences Centre, Toronto, ON, Canada.;Institute for Clinical Evaluative Sciences, Toronto, ON, Canada. ^[4] University of Toronto, Toronto, ON, Canada.;Sunnybrook Health Sciences Centre, Toronto, ON, Canada.;Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.;Ontario Institute for Cancer Research, Toronto, ON, Canada. ^[5] University of Toronto, Toronto, ON, Canada.;University Health Network, Toronto, ON, Canada. ^[6] University of Toronto, Toronto, ON, Canada.;Toronto Health Economics and Health Assessment, Toronto, ON, Canada. ^[7] University of Toronto, Toronto, ON, Canada.;Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.;University Health Network, Toronto, ON, Canada. ^[8] Cancer Care Ontario, Toronto, ON, Canada. ^[9] British Columbia Cancer Agency, Vancouver, BC, Canada.;Canadian Center for Applied Research in Cancer Control, Canada. ^[10] University of Toronto, Toronto, ON, Canada. kelvin.chan@sunnybrook.ca.;Sunnybrook Health Sciences Centre, Toronto, ON, Canada. kelvin.chan@sunnybrook.ca.;Cancer Care Ontario, Toronto, ON, Canada. kelvin.chan@sunnybrook.ca.;Canadian Center for Applied Research in Cancer Control, Canada, . kelvin.chan@sunnybrook.ca. ^[11]

关键词 Cardiovascular outcomes Disease relapse HER2 Overall survival Trastuzumab Trastuzumab-related cardiotoxicity