Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir.-论文-万方医学网

作者： Huicong,Zhou ^[1] ; Zhiliang,He ^[2] ; Changdong,Wang ^[3] ; Tingting,Xie ^[4] ; Lin,Liu ^[5] ; Chuanyang,Liu ^[6] ; Fangzhou,Song ^[7] ; Yongping,Ma ^[8]

作者单位： Molecular Medicine &amp; Cancer Research Center, Department of Biochemistry &amp; Molecular Biology, Chongqing Medical University, Yuzhong District, Yi XueYuan Road, Number 1, Chongqing 400016, China. zhczb@163.com. ^[1] Molecular Medicine &amp; Cancer Research Center, Department of Biochemistry &amp; Molecular Biology, Chongqing Medical University, Yuzhong District, Yi XueYuan Road, Number 1, Chongqing 400016, China. jk0072007@163.com. ^[2] Molecular Medicine &amp; Cancer Research Center, Department of Biochemistry &amp; Molecular Biology, Chongqing Medical University, Yuzhong District, Yi XueYuan Road, Number 1, Chongqing 400016, China. cdwhust@163.com. ^[3] Molecular Medicine &amp; Cancer Research Center, Department of Biochemistry &amp; Molecular Biology, Chongqing Medical University, Yuzhong District, Yi XueYuan Road, Number 1, Chongqing 400016, China. 18716461018@163.com. ^[4] Molecular Medicine &amp; Cancer Research Center, Department of Biochemistry &amp; Molecular Biology, Chongqing Medical University, Yuzhong District, Yi XueYuan Road, Number 1, Chongqing 400016, China. 15086785450@163.com. ^[5] Molecular Medicine &amp; Cancer Research Center, Department of Biochemistry &amp; Molecular Biology, Chongqing Medical University, Yuzhong District, Yi XueYuan Road, Number 1, Chongqing 400016, China. 13883688451@163.com. ^[6] Molecular Medicine &amp; Cancer Research Center, Department of Biochemistry &amp; Molecular Biology, Chongqing Medical University, Yuzhong District, Yi XueYuan Road, Number 1, Chongqing 400016, China. fzsongcq@163.com. ^[7] Molecular Medicine &amp; Cancer Research Center, Department of Biochemistry &amp; Molecular Biology, Chongqing Medical University, Yuzhong District, Yi XueYuan Road, Number 1, Chongqing 400016, China. yongpingm@yahoo.com. ^[8]

主题词动物(Animals);细胞凋亡(Apoptosis);二裂菌属(Bifidobacterium);半胱氨酸天冬氨酸蛋白酶8(Caspase 8);细胞系, 肿瘤(Cell Line, Tumor);细胞因子类(Cytokines);疾病模型, 动物(Disease Models, Animal);更昔洛韦(Ganciclovir);基因表达(Gene Expression);遗传载体(Genetic Vectors);疱疹病毒1型, 人(Herpesvirus 1, Human);人类(Humans);男(雄)性(Male);小鼠(Mice);肿瘤(Neoplasms);信号传导(Signal Transduction);胸苷激酶(Thymidine Kinase);Toll样受体2(Toll-Like Receptor 2);肿瘤负荷(Tumor Burden);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.3390/ijms17060891

PMID 27275821

发布时间 2018-11-13

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Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir.

International journal of molecular sciences

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International journal of molecular sciences

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Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir.

International journal of molecular sciences

相似文献

International journal of molecular sciences

相关期刊

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