Deletion of Gab2 in mice protects against hepatic steatosis and steatohepatitis: a novel therapeutic target for fatty liver disease.-论文-万方医学网

作者： Shuai,Chen ^[1] ; Yujia,Kang ^[1] ; Yan,Sun ^[1] ; Yanhong,Zhong ^[1] ; Yanli,Li ^[1] ; Lijuan,Deng ^[1] ; Jin,Tao ^[1] ; Yang,Li ^[1] ; Yingpu,Tian ^[1] ; Yinan,Zhao ^[1] ; Jianghong,Cheng ^[1] ; Wenjie,Liu ^[1] ; Gen-Sheng,Feng ^[2] ; Zhongxian,Lu ^[3]

作者单位： School of Pharmaceutical Sciences, State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen, Fujian 361005, China. ^[1] Department of Pathology, and Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA zhongxian@xmu.edu.cn gfeng@ucsd.edu. ^[2] School of Pharmaceutical Sciences, State Key Laboratory of Cellular Stress Biology, Xiamen University, Xiamen, Fujian 361005, China zhongxian@xmu.edu.cn gfeng@ucsd.edu. ^[3]

主题词衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);动物(Animals);疾病模型, 动物(Disease Models, Animal);乙醇(Ethanol);脂肪肝(Fatty Liver);GRB2衔接蛋白质(GRB2 Adaptor Protein);基因缺失(Gene Deletion);Hep G2细胞(Hep G2 Cells);肝细胞(Hepatocytes);人类(Humans);脂类(Lipids);肝(Liver);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);模型, 生物学(Models, Biological);分子靶向治疗(Molecular Targeted Therapy);油酸(Oleic Acid);磷蛋白类(Phosphoproteins);预防和防护用药(Protective Agents);蛋白质酪氨酸磷酸酶, 非受体11型(Protein Tyrosine Phosphatase, Non-Receptor Type 11);信号传导(Signal Transduction)

DOI 10.1093/jmcb/mjw028

PMID 27282405

发布时间 2019-12-10

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Deletion of Gab2 in mice protects against hepatic steatosis and steatohepatitis: a novel therapeutic target for fatty liver disease.

Journal of molecular cell biology

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Journal of molecular cell biology

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Deletion of Gab2 in mice protects against hepatic steatosis and steatohepatitis: a novel therapeutic target for fatty liver disease.

Journal of molecular cell biology

相似文献

Journal of molecular cell biology

相关期刊

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