Modulated cellular delivery of anti-VEGF siRNA (bevasiranib) by incorporating supramolecular assemblies of hydrophobically modified polyamidoamine dendrimer in stealth liposomes.
第一作者:
Nasim,Golkar
第一单位:
Pharmaceutics Department, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz 71345, Iran. Electronic address: nassim_golkar@yahoo.com.
作者:
关键词
Anti-VEGF siRNACholesterolDAPI (PubChem CID: 2954)DOPE (PubChem CID: 9546757)DSPC (PubChem CID: 94190)Ethidium bromide (PubChem CID: 14710)G1 PAMAM dendrimer (PubChem CID: 15314332)G2 PAMAM dendrimer (PubChem CID: 58720429)Gene deliveryHEPES (PubChem CID: 23831)N,N-diisopropylethylamine (PubChem CID: 81531)PEG-liposomePoly amidoamine dendrimerPyrene (PubChem CID: 31423)TNBS (PubChem CID: 11045)
医学主题词
细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);树状聚合物(Dendrimers);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物载体(Drug Carriers);药物释放系统(Drug Delivery Systems);人类(Humans);亲水和疏水相互作用(Hydrophobic and Hydrophilic Interactions);脂质体(Liposomes);聚胺类(Polyamines);RNA, 小分子干扰(RNA, Small Interfering);血管内皮生长因子A(Vascular Endothelial Growth Factor A)
DOI
10.1016/j.ijpharm.2016.06.026
PMID
27291973
发布时间
2019-01-11
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