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首页> BMC bioinformatics> Integrating multiple immunogenetic data sources for feature extraction and mining somatic hypermutation patterns: the case of "towards analysis" in chronic lymphocytic leukaemia.

Integrating multiple immunogenetic data sources for feature extraction and mining somatic hypermutation patterns: the case of "towards analysis" in chronic lymphocytic leukaemia.

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作者： Ioannis,Kavakiotis ^[1] ; Aliki,Xochelli ^[2] ; Andreas,Agathangelidis ^[3] ; Grigorios,Tsoumakas ^[4] ; Nicos,Maglaveras ^[5] ; Kostas,Stamatopoulos ^[2] ; Anastasia,Hadzidimitriou ^[6] ; Ioannis,Vlahavas ^[2] ; Ioanna,Chouvarda ^[3]

作者单位： Department of Informatics, Aristotle University of Thessaloniki, Thessaloniki, Greece. ikavak@csd.auth.gr. ^[1] Institute of Applied Biosciences, CERTH, Thessaloniki, Greece. ^[2] Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. ^[3] Division of Molecular Oncology and Department of Onco-Hematology, San Raffaele Scientific Institute, Milan, Italy. ^[4] Department of Informatics, Aristotle University of Thessaloniki, Thessaloniki, Greece. ^[5] Lab of Computing and Medical Informatics, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece. ^[6]

关键词 CLL Chronic lymphocytic leukaemia Data integration Feature extraction List aggregation Mutation patterns, somatic hypermutation SHM

主题词成年人(Adult);数据库, 遗传学(Databases, Genetic);女(雌)性(Female);生殖细胞系突变(Germ-Line Mutation);人类(Humans);免疫遗传学(Immunogenetics);免疫球蛋白可变区(Immunoglobulin Variable Region);免疫球蛋白类(Immunoglobulins);白血病, 淋巴细胞, 慢性, B细胞(Leukemia, Lymphocytic, Chronic, B-Cell);体细胞高突变, 免疫球蛋白(Somatic Hypermutation, Immunoglobulin)

DOI 10.1186/s12859-016-1044-3

PMID 27295298

发布时间 2018-12-02

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BMC bioinformatics

2016年17 Suppl 5卷

173页

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BMC bioinformatics

2016年17 Suppl 5卷

173页

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