Eudistomin C, an Antitumor and Antiviral Natural Product, Targets 40S Ribosome and Inhibits Protein Translation.

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作者： Yu,Ota ^[1] ; Takumi,Chinen ^[1] ; Keisuke,Yoshida ^[1] ; Shun,Kudo ^[1] ; Yoko,Nagumo ^[1] ; Yuh,Shiwa ^[2] ; Ryosuke,Yamada ^[3] ; Hirotatsu,Umihara ^[4] ; Kotaro,Iwasaki ^[4] ; Hiroshi,Masumoto ^[5] ; Satoshi,Yokoshima ^[5] ; Hirofumi,Yoshikawa ^[6] ; Tohru,Fukuyama ^[7] ; Junichi,Kobayashi ^[4] ; Takeo,Usui ^[2]

作者单位： Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8572, Japan. ^[1] NODAI Genome Research Center, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo, 156-8502, Japan. ^[2] Division of Biobank and Data Management, Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Yahaba-cho, Shiwa-gun, Iwate, 028-3694, Japan. ^[3] Graduate School of Pharmaceutical Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan. ^[4] Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. ^[5] Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, 980-8577, Japan. ^[6] Biomedical Research Support Center, Nagasaki University School of Medicine, 1-12-4 Sakamoto, Nagasaki, Nagasaki, 852-8523, Japan. ^[7] Department of Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo, 156-8502, Japan. ^[8] Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, 060-0812, Japan. ^[9] Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8572, Japan. usui.takeo.kb@u.tsukuba.ac.jp. ^[10]

关键词 eudistomin?C multidrug sensitive strain protein translation uS11 yeast genetics