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首页> Journal of controlled release : official journal of the Controlled Release Society> Progress in the development of lipopolyplexes as efficient non-viral gene delivery systems.

Progress in the development of lipopolyplexes as efficient non-viral gene delivery systems.

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作者： Mehdi,Rezaee ^[1] ; Reza Kazemi,Oskuee ^[2] ; Hooriyeh,Nassirli ^[3] ; Bizhan,Malaekeh-Nikouei ^[4]

作者单位： Department of Medical Biotechnology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: RezaeiM911@mums.ac.ir. ^[1] Targeted Drug Delivery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: OskueeKR@mums.ac.ir. ^[2] Pharmaceutical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: Nasirleeh1@mums.ac.ir. ^[3] Nanotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: MalaekehB@mums.ac.ir. ^[4]

关键词 CHEMS, cholesteryl hemisuccinate (PubChem CID: 65082);Chol, cholesterol (PubChem CID: 5997);DDAB, dimethyldioctadecylammonium bromide (PubChem CID: 77293);DMPE, dimyristoylphosphatidylethanolamine (PubChem CID: 114944);DMPG, 1,2-ditetradecanoyl-sn-glycero-3-phospho-1′-rac-glycerol sodium salt (PubChem CID: 71311889);DODAC, dioleyldimethylammonium chloride (PubChem CID: 6436349);DOPC, 1,2-dioleoyl-sn-glycero-3-phosphocholine (PubChem CID: 10350317);DOPE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (PubChem CID: 44251425);DOTAP, 1,2-dioleoyl-3-trimethylammonium-propane (PubChem CID: 107898);DOTMA, N-[1-(2,3-dioleyloxy) propyl]-N,N,N-trimethlylammonium chloride (PubChem CID: 6438350);DPPE, 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (PubChem CID: 46907860);DPTAP, 1,2-dipalmitoyl-3-trimethylammonium-propane (PubChem CID: 107898);DTDTMA, ditetradecyl trimethyl ammonium (PubChem CID: 14251);Gene delivery Gene therapy HZN, pyridylhydrazone (PubChem CID: 6436327);IL-2 and 12, interleukin-2 and 12 (PubChem CID: 130138);Lipopolyplexes Non-viral vectors PEG, poly(ethylene glycol) (PubChem CID: 174);Rhod-DOPE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(lissamine rhodamine B sulfonyl) ammonium salt (PubChem CID: 44251425)

主题词动物(Animals);化学, 药物(Chemistry, Pharmaceutical);基因转移技术(Gene Transfer Techniques);人类(Humans);脂类(Lipids);脂质体(Liposomes);纳米粒子(Nanoparticles);核酸类(Nucleic Acids);肽类(Peptides);聚合物(Polymers);转染(Transfection)

DOI 10.1016/j.jconrel.2016.06.023

PMID 27317365

发布时间 2022-04-08

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Journal of controlled release

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