Molecular analysis distinguishes metastatic disease from second cancers in patients with retinoblastoma.

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第一作者： Hilary,Racher

第一单位： Impact Genetics, Bowmanville, Ontario L1C 3K5, Canada.

作者： Hilary,Racher ^[1] ; Sameh,Soliman ^[2] ; Bob,Argiropoulos ^[3] ; Helen S L,Chan ^[4] ; Brenda L,Gallie ^[4] ; Renée,Perrier ^[3] ; Donco,Matevski ^[1] ; Diane,Rushlow ^[1] ; Beata,Piovesan ^[1] ; Furqan,Shaikh ^[4] ; Heather,MacDonald ^[4] ; Timothy W,Corson ^[5]

作者单位： Impact Genetics, Bowmanville, Ontario L1C 3K5, Canada. ^[1] Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada; Ophthalmology Department, Faculty of Medicine, University of Alexandria, Alexandria, Egypt. ^[2] Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta T2N 4N1, Canada. ^[3] Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada. ^[4] Eugene and Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Electronic address: tcorson@iu.edu. ^[5]

关键词 Retinoblastoma differential diagnosis inverse PCR metastasis mutation detection second primary tumor

主题词儿童, 学龄前(Child, Preschool);染色体断裂(Chromosome Breakage);密码子, 无义(Codon, Nonsense);诊断, 鉴别(Diagnosis, Differential);致命性结局(Fatal Outcome);女(雌)性(Female);基因剂量(Gene Dosage);人类(Humans);婴儿(Infant);男(雄)性(Male);肿瘤转移(Neoplasm Metastasis);肿瘤, 继发原发性(Neoplasms, Second Primary);聚合酶链反应(Polymerase Chain Reaction);视网膜肿瘤(Retinal Neoplasms);视网膜母细胞瘤(Retinoblastoma);视网膜母细胞瘤结合蛋白类(Retinoblastoma Binding Proteins);泛素蛋白连接酶类(Ubiquitin-Protein Ligases)

DOI 10.1016/j.cancergen.2016.06.001

PMID 27318443

发布时间 2019-06-10

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Cancer genetics

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Molecular analysis distinguishes metastatic disease from second cancers in patients with retinoblastoma.

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Molecular analysis distinguishes metastatic disease from second cancers in patients with retinoblastoma.

Cancer genetics

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Cancer genetics

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