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Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis.

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第一作者： Eric J,Solís

第一单位： Department of Molecular and Cellular Biology, Northwest Labs, Harvard University, Cambridge, MA 02138, USA; Systems Biology PhD Program, Harvard University, Cambridge, MA 02138, USA.

作者： Eric J,Solís ^[1] ; Jai P,Pandey ^[2] ; Xu,Zheng ^[2] ; Dexter X,Jin ^[3] ; Piyush B,Gupta ^[4] ; Edoardo M,Airoldi ^[5] ; David,Pincus ^[6] ; Vladimir,Denic ^[7]

作者单位： Department of Molecular and Cellular Biology, Northwest Labs, Harvard University, Cambridge, MA 02138, USA; Systems Biology PhD Program, Harvard University, Cambridge, MA 02138, USA. ^[1] Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA. ^[2] Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. ^[3] Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA 02142, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. ^[4] Department of Statistics, Harvard University, Cambridge, MA 02138, USA. ^[5] Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA. Electronic address: pincus@wi.mit.edu. ^[6] Department of Molecular and Cellular Biology, Northwest Labs, Harvard University, Cambridge, MA 02138, USA. Electronic address: vdenic@mcb.harvard.edu. ^[7]