CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia.-论文-万方医学网

作者： Jihua,Qiu ^[1] ; Xuena,Liu ^[1] ; Xiaoqing,Li ^[2] ; Xu,Zhang ^[1] ; Panpan,Han ^[1] ; Hai,Zhou ^[1] ; Linlin,Shao ^[1] ; Yu,Hou ^[1] ; Yanan,Min ^[1] ; Zhangyuan,Kong ^[1] ; Yawen,Wang ^[1] ; Yu,Wei ^[1] ; Xinguang,Liu ^[1] ; Heyu,Ni ^[3] ; Jun,Peng ^[1] ; Ming,Hou ^[4]

作者单位： Department of Hematology, Qilu Hospital, Shandong University, Jinan, China. ^[1] School of Medicine, Zhejiang University, Hangzhou, China. ^[2] Canadian Blood Services and the Department of Laboratory Medicine and Pathobiology, Keenan Research Centre in the Li Ka Shing Knowledge Institute of St. Michael's Hospital, University of Toronto, Toronto, Canada. ^[3] Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital, Shandong University, Jinan, China. ^[4] Shandong Provincial Key Laboratory of Immunohematology, Qilu Hospital, Shandong University, Jinan, China. ^[5]

主题词青少年(Adolescent);成年人(Adult);老年人(Aged);动物(Animals);去唾液酸糖蛋白受体(Asialoglycoprotein Receptor);血小板(Blood Platelets);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);细胞系, 肿瘤(Cell Line, Tumor);女(雌)性(Female);Hep G2细胞(Hep G2 Cells);肝细胞(Hepatocytes);人类(Humans);肝(Liver);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);中年人(Middle Aged);神经氨酸酶(Neuraminidase);吞噬作用(Phagocytosis);紫癜, 血小板减少性, 特发性(Purpura, Thrombocytopenic, Idiopathic);青年人(Young Adult)

DOI 10.1038/srep27445

PMID 27321376

发布时间 2018-11-13

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CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia.

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CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia.

Scientific reports

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Scientific reports

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