Aldehyde dehydrogenase 2 protects human umbilical vein endothelial cells against oxidative damage and increases endothelial nitric oxide production to reverse nitroglycerin tolerance.
第一作者:
X Y,Hu
第一单位:
Department of Hematology, Affiliated Hospital of GuiZhou Medical University, Guiyang, China.;Key Laboratory of Hematological Disease Diagnostic & Treat Centre of GuiZhou Province, Guiyang, China.;GuiZhou Province Hematopoietic Stem Cell Transplantation Center, Affiliated Hospital of GuiZhou Medical University, Guiyang, China.
作者:
医学主题词
药物耐受性(Drug Tolerance);内皮细胞(Endothelial Cells);基因表达调控(Gene Expression Regulation);血红素加氧酶-1(Heme Oxygenase-1);人类(Humans);一氧化氮(Nitric Oxide);硝酸甘油(Nitroglycerin);氧化性应激(Oxidative Stress);磷酰化(Phosphorylation);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);RNA, 信使(RNA, Messenger)
DOI
10.4238/gmr.15027822
PMID
27323160
发布时间
2017-02-08
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