Experimental and Theoretical Investigation of Multispecies Oral Biofilm Resistance to Chlorhexidine Treatment.

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作者： Ya,Shen ^[1] ; Jia,Zhao ^[2] ; César,de la Fuente-Núñez ^[3] ; Zhejun,Wang ^[4] ; Robert E W,Hancock ^[1] ; Clive R,Roberts ^[3] ; Jingzhi,Ma ^[5] ; Jun,Li ^[6] ; Markus,Haapasalo ^[7] ; Qi,Wang ^[1]

作者单位： Division of Endodontics, Department of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, British Columbia, V6T 1Z3 Canada. ^[1] Department of Mathematics, University of South Carolina, Columbia, SC 29208, USA. ^[2] Centre for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, Vancouver, V6T 1Z3 Canada. ^[3] Synthetic Biology Group, MIT Synthetic Biology Center, Research Laboratory of Electronics, Department of Biological Engineering, Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. ^[4] Department of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, British Columbia, V6T 1Z3 Canada. ^[5] Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 China. ^[6] School of Mathematical Sciences, Nankai University, Tianjin 300071, China. ^[7] Beijing Computational Science Research Center, Beijing 100193, China and School of Materials Science and Engineering, Nankai University, Tianjin 300071, China. ^[8]

主题词抗菌药(Anti-Bacterial Agents);生物膜(Biofilms);氯己定(Chlorhexidine);人类(Humans);微生物生存能力(Microbial Viability);显微镜检查, 共焦(Microscopy, Confocal);口腔疾病(Mouth Diseases);群体感应(Quorum Sensing);表面特性(Surface Properties)

DOI 10.1038/srep27537

PMID 27325010

发布时间 2022-03-11

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