DJ-1 deficiency impairs glutamate uptake into astrocytes via the regulation of flotillin-1 and caveolin-1 expression.

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作者： Jin-Mo,Kim ^[1] ; Seon-Heui,Cha ^[2] ; Yu Ree,Choi ^[1] ; Ilo,Jou ^[2] ; Eun-Hye,Joe ^[1] ; Sang Myun,Park ^[2]

作者单位： Department of Pharmacology, Ajou University School of Medicine, Suwon, Korea. ^[1] Chronic Inflammatory Disease Research Center, Ajou University School of Medicine, Suwon, Korea. ^[2] Neuroscience Graduate Program, Department of Biomedical Sciences, Ajou University School of Medicine, Suwon, Korea. ^[3]

主题词动物(Animals);星形细胞(Astrocytes);脑(Brain);窖蛋白1(Caveolin 1);中枢神经系统(Central Nervous System);胆固醇(Cholesterol);胞吞作用(Endocytosis);兴奋性氨基酸转运子2(Excitatory Amino Acid Transporter 2);基因表达调控(Gene Expression Regulation);谷氨酸(Glutamic Acid);内环境稳定(Homeostasis);膜微区(Membrane Microdomains);膜蛋白质类(Membrane Proteins);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);突变(Mutation);蛋白质结合(Protein Binding)

DOI 10.1038/srep28823

PMID 27346864

发布时间 2018-11-13

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DJ-1 deficiency impairs glutamate uptake into astrocytes via the regulation of flotillin-1 and caveolin-1 expression.

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DJ-1 deficiency impairs glutamate uptake into astrocytes via the regulation of flotillin-1 and caveolin-1 expression.

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