首页> Breast cancer research : BCR> Efficacy and safety of palbociclib in combination with letrozole as first-line treatment of ER-positive, HER2-negative, advanced breast cancer: expanded analyses of subgroups from the randomized pivotal trial PALOMA-1/TRIO-18.

Efficacy and safety of palbociclib in combination with letrozole as first-line treatment of ER-positive, HER2-negative, advanced breast cancer: expanded analyses of subgroups from the randomized pivotal trial PALOMA-1/TRIO-18.

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第一作者： Richard S,Finn

第一单位： Department of Medicine, Division of Hematology/Oncology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA. RFinn@mednet.ucla.edu.

作者： Richard S,Finn ^[1] ; John P,Crown ^[2] ; Johannes,Ettl ^[3] ; Marcus,Schmidt ^[4] ; Igor M,Bondarenko ^[5] ; Istvan,Lang ^[6] ; Tamas,Pinter ^[7] ; Katalin,Boer ^[8] ; Ravindranath,Patel ^[9] ; Sophia,Randolph ^[10] ; Sindy T,Kim ^[10] ; Xin,Huang ^[10] ; Patrick,Schnell ^[11] ; Sashi,Nadanaciva ^[12] ; Cynthia Huang,Bartlett ^[13] ; Dennis J,Slamon ^[14]

作者单位： Department of Medicine, Division of Hematology/Oncology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA. RFinn@mednet.ucla.edu. ^[1] Irish Cooperative Oncology Research Group, Dublin, Ireland. ^[2] Technical University of Munich, Munich, Germany. ^[3] University Hospital Mainz, Mainz, Germany. ^[4] Dnipropetrovsk Medical Academy, City Multiple-Discipline Clinical Hospital, Dnipropetrovsk, Ukraine. ^[5] Orszagos Onkologiai Intezet, Budapest, Hungary. ^[6] Petz Aladar Megyei Oktato Korhaz, Gyor, Hungary. ^[7] Department of Medical Oncology, Szent Margit Korhaz, Onkologia, Budapest, Hungary. ^[8] Comprehensive Blood and Cancer Center, Bakersfield, CA, USA. ^[9] Pfizer Oncology, La Jolla, CA, USA. ^[10] Pfizer Oncology, New York, NY, USA. ^[11] Pfizer Oncology, Groton, CT, USA. ^[12] Pfizer Oncology, Collegeville, PA, USA. ^[13] Department of Medicine, Division of Hematology/Oncology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA. ^[14]

关键词 Breast cancer Cyclin-dependent kinase Estrogen receptor-positive HER2-negative Neutropenia