Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression.

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作者： Bernhard,Englinger ^[1] ; Daniela,Lötsch ^[1] ; Christine,Pirker ^[1] ; Thomas,Mohr ^[1] ; Sushilla,van Schoonhoven ^[1] ; Bernd,Boidol ^[2] ; Charles-Hugues,Lardeau ^[2] ; Melanie,Spitzwieser ^[3] ; Pál,Szabó ^[4] ; Petra,Heffeter ^[1] ; Irene,Lang ^[5] ; Margit,Cichna-Markl ^[3] ; Bettina,Grasl-Kraupp ^[1] ; Brigitte,Marian ^[1] ; Michael,Grusch ^[1] ; Stefan,Kubicek ^[2] ; Gergely,Szakács ^[1] ; Walter,Berger ^[6]

作者单位： Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Austria. ^[1] CeMM Research Center for Molecular Medicine of The Austrian Academy of Sciences, Vienna, Austria. ^[2] Department of Analytical Chemistry, University of Vienna, Vienna, Austria. ^[3] Institute of Organic Chemistry, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary. ^[4] Division of Cardiology, Department of Medicine II, Medical University of Vienna, Vienna, Austria. ^[5] Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary. ^[6]

关键词 ABCB1 FGFR1 endothelin-A receptor nintedanib small cell lung cancer