Inactivation of oncogenic cAMP-specific phosphodiesterase 4D by miR-139-5p in response to p53 activation.
第一作者:
Bo,Cao
第一单位:
Department of Biochemistry and Molecular Biology, Tulane Cancer Center, Tulane University School of Medicine, New Orleans, United States.
作者:
主题词
动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);结直肠肿瘤(Colorectal Neoplasms);环核苷酸磷酸二酯酶类, 4型(Cyclic Nucleotide Phosphodiesterases, Type 4);疾病模型, 动物(Disease Models, Animal);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);小鼠, 近交BALB C(Mice, Inbred BALB C);微RNAs(MicroRNAs);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)
DOI
10.7554/eLife.15978
PMID
27383270
发布时间
2018-11-13
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