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Circulating Extracellular Vesicles Contain miRNAs and are Released as Early Biomarkers for Cardiac Injury.

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第一作者： Janine C,Deddens

第一单位： Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.;Netherlands Heart Institute (ICIN), Utrecht, The Netherlands.

作者： Janine C,Deddens ^[1] ; Krijn R,Vrijsen ^[2] ; Johanna M,Colijn ^[2] ; Martinus I,Oerlemans ^[2] ; Corina H G,Metz ^[3] ; Els J,van der Vlist ^[4] ; Esther N M,Nolte-'t Hoen ^[4] ; Krista,den Ouden ^[5] ; Sanne J,Jansen Of Lorkeers ^[2] ; Tycho I G,van der Spoel ^[2] ; Stefan,Koudstaal ^[2] ; Ger J,Arkesteijn ^[4] ; Marca H M,Wauben ^[4] ; Linda W,van Laake ^[3] ; Pieter A,Doevendans ^[6] ; Steven A J,Chamuleau ^[6] ; Joost P G,Sluijter ^[7]

作者单位： Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.;Netherlands Heart Institute (ICIN), Utrecht, The Netherlands. ^[1] Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands. ^[2] Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.;UMC Utrecht Regenerative Medicine Center, University Medical Center Utrecht, Utrecht, The Netherlands. ^[3] Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. ^[4] UMC Utrecht Regenerative Medicine Center, University Medical Center Utrecht, Utrecht, The Netherlands. ^[5] Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.;UMC Utrecht Regenerative Medicine Center, University Medical Center Utrecht, Utrecht, The Netherlands.;Netherlands Heart Institute (ICIN), Utrecht, The Netherlands. ^[6] Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands. J.Sluijter@umcutrecht.nl.;UMC Utrecht Regenerative Medicine Center, University Medical Center Utrecht, Utrecht, The Netherlands. J.Sluijter@umcutrecht.nl.;Netherlands Heart Institute (ICIN), Utrecht, The Netherlands. J.Sluijter@umcutrecht.nl.;Department of Cardiology, Experimental Cardiology Laboratory, University Medical Center Utrecht, Heidelberglaan 100, PO Box 85500, 3508 GA, Utrecht, The Netherlands. J.Sluijter@umcutrecht.nl. ^[7]

关键词 Biomarkers Circulating microRNA Exosomes Extracellular vesicles Myocardial infarction